Table 2.

Plasma protein phenotype of BKB2R−/− mice


Assay

Control, U/mL

BKB2R−/−, U/mL

P
Antithrombin   1.41 ± 11*  1.44 ± 5   .81  
Plasminogen   1.52 ± 6.3   1.54 ± 8.7   .85  
tPA   0.25 ± 0.12   0.34 ± 0.33   .64  
PAI-1   7.56 ± 0.98   10.7 ± 0.92   <.04  
Factor XI   0.39 ± 0.05   0.23 ± 0.03   <.02  
Prekallikrein   0.23 ± 0.015   0.29 ± 0.012   <.006  
HK   0.14 ± 0.02   0.12 ± 0.01   .49  
Factor XII
 
0.8 ± 0.17
 
1.14 ± 0.11
 
.13
 

Assay

Control, U/mL

BKB2R−/−, U/mL

P
Antithrombin   1.41 ± 11*  1.44 ± 5   .81  
Plasminogen   1.52 ± 6.3   1.54 ± 8.7   .85  
tPA   0.25 ± 0.12   0.34 ± 0.33   .64  
PAI-1   7.56 ± 0.98   10.7 ± 0.92   <.04  
Factor XI   0.39 ± 0.05   0.23 ± 0.03   <.02  
Prekallikrein   0.23 ± 0.015   0.29 ± 0.012   <.006  
HK   0.14 ± 0.02   0.12 ± 0.01   .49  
Factor XII
 
0.8 ± 0.17
 
1.14 ± 0.11
 
.13
 

TPA indicates tissue plasminogen activator; PAI-1, plasminogen activator inhibitor-1; HK, high-molecular-weight kininogen.

*

These data are the mean plus or minus SD of 7 or more individual experiments.

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