Characteristics of CLL patients and control subjects
. | Sweden . | . | Denmark . | . | ||
|---|---|---|---|---|---|---|
| Variable . | Patients . | Control subjects . | Patients . | Control subjects . | ||
| Total number | 5927 | 11 796 | 1837 | 4862 | ||
| Age in y at CLL diagnosis, median (interquartile range) | 69 (61-76) | NA | 62 (54-69) | NA | ||
| Age group at CLL diagnosis, n (%) | ||||||
| Young-adult onset CLL, 50 years or younger | 380 (6) | 761 (7) | 301 (16) | 1016 (21) | ||
| Midlife onset CLL, 51-70 years | 2904 (49) | 5786 (49) | 1180 (64) | 3208 (66) | ||
| Late onset CLL, older than 70 years | 2643 (45) | 5249 (44) | 356 (20) | 638 (13) | ||
| Sex, n (%) | ||||||
| Male | 3854 (65) | 7660 (65) | 1287 (70) | 3403 (70) | ||
| Female | 2073 (35) | 4136 (35) | 550 (30) | 1459 (30) | ||
| Year of CLL diagnosis, median (interquartile range) | 1985 (1977-1993) | NA | 1990 (1984-1994) | NA | ||
| First-degree relatives, n (mean no. per proband) | ||||||
| Parents | 1101 (0.2) | 2200 (0.2) | 121 (0.1) | 414 (0.1) | ||
| Siblings | 930 (0.2) | 1870 (0.2) | 80 (0.1) | 218 (0.1) | ||
| Offspring | 12 340 (2.1) | 24 873 (2.1) | 3419 (1.9) | 9813 (2.1) | ||
. | Sweden . | . | Denmark . | . | ||
|---|---|---|---|---|---|---|
| Variable . | Patients . | Control subjects . | Patients . | Control subjects . | ||
| Total number | 5927 | 11 796 | 1837 | 4862 | ||
| Age in y at CLL diagnosis, median (interquartile range) | 69 (61-76) | NA | 62 (54-69) | NA | ||
| Age group at CLL diagnosis, n (%) | ||||||
| Young-adult onset CLL, 50 years or younger | 380 (6) | 761 (7) | 301 (16) | 1016 (21) | ||
| Midlife onset CLL, 51-70 years | 2904 (49) | 5786 (49) | 1180 (64) | 3208 (66) | ||
| Late onset CLL, older than 70 years | 2643 (45) | 5249 (44) | 356 (20) | 638 (13) | ||
| Sex, n (%) | ||||||
| Male | 3854 (65) | 7660 (65) | 1287 (70) | 3403 (70) | ||
| Female | 2073 (35) | 4136 (35) | 550 (30) | 1459 (30) | ||
| Year of CLL diagnosis, median (interquartile range) | 1985 (1977-1993) | NA | 1990 (1984-1994) | NA | ||
| First-degree relatives, n (mean no. per proband) | ||||||
| Parents | 1101 (0.2) | 2200 (0.2) | 121 (0.1) | 414 (0.1) | ||
| Siblings | 930 (0.2) | 1870 (0.2) | 80 (0.1) | 218 (0.1) | ||
| Offspring | 12 340 (2.1) | 24 873 (2.1) | 3419 (1.9) | 9813 (2.1) | ||
CLL indicates chronic lymphocytic leukemia; NA, not applicable.