Table 1.

Genes up-regulated in Hoxa9/Meis1-transduced cells versus control


Fold change

Gene

Name/comment

Affymetrix ID
7.1  Hoxa9  Homeobox A9*  1421579_at  
6.8  Arhj  ras homolog gene family, member J, small GTPase   1418892_at  
4.0  LOC235036  Peter pan homolog; second-step splicing factor 1   1423703_at  
3.8  Klf9  Kruppel-like factor 9, GC box binding transcription factor   1456341_a_at  
3.6  Tst  Thiosulfate sulfurtransferase, mitochondrial   1448609_at  
3.4  AW545363  CD40 ligand-activated specific transcript 3   1425373_a_at  
3.4  Myb  Myeloblastosis oncogene   1422734_a_at  
3.3  Nucb2  Nucleobindin 2, overexpressed in non-Hodgkin lymphoma   1418355_at  
3.3  Cd28  CD28 antigen, T-cell marker   1437025_at  
3.2  Mylk  Myosin, light polypeptide kinase   1425505_at  
3.1  Schip 1  Schwannomin interacting protein 1, neural cell specific   1423025_a_at  
2.8  Gstm 1  Glutathione S-transferase μ1, myb target gene   1448330_at  
2.7  Ide  Insulin degrading enzyme   1453988_a_at  
2.6  Trip 13  Thyroid hormone receptor interactor 13   1429294_at  
2.6  Pde7a  Phosphodiesterase 7A   1451839_a_at  
2.5  Enc 1  Ectodermal-neural cortex 1   1454904_at  
2.5  Bcat 1  Branched chain aminotransferase 1, cytosolic   1450871_a_at  
2.5  Nedd4  Neural precursor expressed, developmentally down-regulated   1450431_a_at  
2.5
 
Dutp
 
Deoxyuridine triphosphatase
 
1419270_a_at
 

Fold change

Gene

Name/comment

Affymetrix ID
7.1  Hoxa9  Homeobox A9*  1421579_at  
6.8  Arhj  ras homolog gene family, member J, small GTPase   1418892_at  
4.0  LOC235036  Peter pan homolog; second-step splicing factor 1   1423703_at  
3.8  Klf9  Kruppel-like factor 9, GC box binding transcription factor   1456341_a_at  
3.6  Tst  Thiosulfate sulfurtransferase, mitochondrial   1448609_at  
3.4  AW545363  CD40 ligand-activated specific transcript 3   1425373_a_at  
3.4  Myb  Myeloblastosis oncogene   1422734_a_at  
3.3  Nucb2  Nucleobindin 2, overexpressed in non-Hodgkin lymphoma   1418355_at  
3.3  Cd28  CD28 antigen, T-cell marker   1437025_at  
3.2  Mylk  Myosin, light polypeptide kinase   1425505_at  
3.1  Schip 1  Schwannomin interacting protein 1, neural cell specific   1423025_a_at  
2.8  Gstm 1  Glutathione S-transferase μ1, myb target gene   1448330_at  
2.7  Ide  Insulin degrading enzyme   1453988_a_at  
2.6  Trip 13  Thyroid hormone receptor interactor 13   1429294_at  
2.6  Pde7a  Phosphodiesterase 7A   1451839_a_at  
2.5  Enc 1  Ectodermal-neural cortex 1   1454904_at  
2.5  Bcat 1  Branched chain aminotransferase 1, cytosolic   1450871_a_at  
2.5  Nedd4  Neural precursor expressed, developmentally down-regulated   1450431_a_at  
2.5
 
Dutp
 
Deoxyuridine triphosphatase
 
1419270_a_at
 

Listed are genes (excluding ESTs) with a change greater than 2.5-fold. If genes were represented by multiple probe sets on the array only the probe set with the highest change in expression level is shown.

*

The expression of Meis 1 could not be detected on the array since all Meis-specific probe sets are located in the 3′ UTR that was not present in the expression construct.

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