Table 1.

Glycoprotein expression in α2A–/– mice


Glycoprotein

Wild-type mice

α2A-/- mice
GPVI   49.1 ± 2.3   48.6 ± 3.2  
Integrin α∥β3   396.1 ± 83.7   353.4 ± 46.6  
GPV   264.6 ± 38.6   269.4 ± 26.4  
GPlbα   641.8 ± 128.1   656.0 ± 71.4  
GPIX   433.4 ± 60.4   405.6 ± 39.9  
Integrin α2   38.2 ± 2.3   36.6 ± 1.9  
Integrin β1   147.0 ± 38.8   138.1 ± 27.3  
CD9
 
1225.4 ± 106.8
 
1192.5 ± 85.7
 

Glycoprotein

Wild-type mice

α2A-/- mice
GPVI   49.1 ± 2.3   48.6 ± 3.2  
Integrin α∥β3   396.1 ± 83.7   353.4 ± 46.6  
GPV   264.6 ± 38.6   269.4 ± 26.4  
GPlbα   641.8 ± 128.1   656.0 ± 71.4  
GPIX   433.4 ± 60.4   405.6 ± 39.9  
Integrin α2   38.2 ± 2.3   36.6 ± 1.9  
Integrin β1   147.0 ± 38.8   138.1 ± 27.3  
CD9
 
1225.4 ± 106.8
 
1192.5 ± 85.7
 

Platelet glycoprotein expression of wild-type and α2A adrenergic knockout mice as determined by flow cytometry. Results are expressed as mean ± SD fluorescence for groups of 6 mice.

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