Table 1.

Allele frequencies of the CPB2 polymorphisms in the European white and African samples


Polymorphisms

Frequency in European whites

Frequency in Africans

Test,*P value
–2599C>G   0.51/0.49   0.43/0.57   .041  
–2345-–2344insG   0.69/0.31   0.71/0.29   .604  
–1925T>C   –   0.92/0.08   –  
–1690A>G   0.71/0.29   0.77/0.23   .121  
–1102G>T   0.71/0.29   0.79/0.21   .017  
–438G>A   0.71/0.29   0.75/0.25   .239  
310C>T   0.69/0.31   0.88/0.12   < .001  
A147T   0.75/0.25   0.67/0.33   .035  
663G>A   0.71/0.29   0.89/0.11   < .001  
678T>C   0.71/0.29   0.66/0.34   .196  
T3251   0.67/0.33   0.89/0.11   < .001  
1542C>G   0.70/0.30   0.89/0.11   < .001  
1583T>A
 
0.70/0.30
 
0.60/0.40
 
.013
 

Polymorphisms

Frequency in European whites

Frequency in Africans

Test,*P value
–2599C>G   0.51/0.49   0.43/0.57   .041  
–2345-–2344insG   0.69/0.31   0.71/0.29   .604  
–1925T>C   –   0.92/0.08   –  
–1690A>G   0.71/0.29   0.77/0.23   .121  
–1102G>T   0.71/0.29   0.79/0.21   .017  
–438G>A   0.71/0.29   0.75/0.25   .239  
310C>T   0.69/0.31   0.88/0.12   < .001  
A147T   0.75/0.25   0.67/0.33   .035  
663G>A   0.71/0.29   0.89/0.11   < .001  
678T>C   0.71/0.29   0.66/0.34   .196  
T3251   0.67/0.33   0.89/0.11   < .001  
1542C>G   0.70/0.30   0.89/0.11   < .001  
1583T>A
 
0.70/0.30
 
0.60/0.40
 
.013
 

For European whites, n = 123; for Africans, n = 170. – indicates not applicable

*

Test for a difference in allele frequency between European whites and Africans

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