Estrus cyclicity and parity in 5 female CLAD dogs after nonmyeloablative conditioning for SCT
Dog . | Source of HSCs . | Time after SCT, y . | Interestrus interval, d . | No. of cycles . | Pregnancies after SCT (puppies) . |
|---|---|---|---|---|---|
| F1*† | BM | 3 | 249 | 4 | 1 (12) |
| F2† | BM | 3 | 337 | 3 | 1 (7) |
| F3* | PBSCs | 3 | 227 | 3 | 0 |
| F4† | PBSCs | 3 | 213 | 4 | 1 (11) |
| F5 | BM | 2 | 235 | 2 | 1 (6) |
Dog . | Source of HSCs . | Time after SCT, y . | Interestrus interval, d . | No. of cycles . | Pregnancies after SCT (puppies) . |
|---|---|---|---|---|---|
| F1*† | BM | 3 | 249 | 4 | 1 (12) |
| F2† | BM | 3 | 337 | 3 | 1 (7) |
| F3* | PBSCs | 3 | 227 | 3 | 0 |
| F4† | PBSCs | 3 | 213 | 4 | 1 (11) |
| F5 | BM | 2 | 235 | 2 | 1 (6) |
The conditioning regimen was 200 cGy TBI for each dog
F indicates female; other abbreviations are explained in Table 1
F1 and F3 did not conceive or had an early loss of the pregnancy after their first breeding. The sires used were a male conditioned with busulfan and a normal dog. F1 conceived on her second breeding and delivered a healthy litter. F3 has not been rebred
Litters sired by males that had received transplants, producing 100% affected progeny