Table 3.

Summary of interphase FISH results of Amp1q21 in patients with MGUS, SMM, newly diagnosed MM, and relapsed MM




Amp1q21 (%)
MGUS  
   Total   0/14 (0)  
   Progression, +   0/1 (0)  
   Progression, –   0/13 (0)  
SMM  
   Total   14/31 (45)  
   Progression, +   10/12 (83)  
   Progression, –   4/19 (21)  
MM  
   At diagnosis   205/479 (43)  
   At relapse
 
33/45 (72)
 



Amp1q21 (%)
MGUS  
   Total   0/14 (0)  
   Progression, +   0/1 (0)  
   Progression, –   0/13 (0)  
SMM  
   Total   14/31 (45)  
   Progression, +   10/12 (83)  
   Progression, –   4/19 (21)  
MM  
   At diagnosis   205/479 (43)  
   At relapse
 
33/45 (72)
 

The median follow-up of patients with MGUS and SMM was 22 months (range, 1 to 88) and 47 months (range, 1 to 123), respectively. P < .001 for SMM progression, +, versus SMM progression, –. P < .001 for MM at diagnosis versus MM at relapse. P = .002 for total MGUS versus total MM

NA indicates not applicable

Close Modal

or Create an Account

Close Modal
Close Modal