Steady-state peripheral blood hematology
Hematologic parameter . | +/+ . | −/− . |
---|---|---|
White blood cell, per μL | 10 000 ± 2 800 | 9 000 ± 2 500 |
Absolute lymphocyte count, per μL | 8 000 ± 1 600 | 7 000 ± 1 900 |
Absolute neutrophil count, per μL | 1 500 ± 300 | 1 400 ± 400 |
Absolute monocyte count, per μL | 600 ± 100 | 700 ± 200 |
Red blood cell, × 103/μL | 3 000 ± 100 | 3 000 ± 400 |
Hematocrit, % | 52 ± 3 | 51±7 |
Hematologic parameter . | +/+ . | −/− . |
---|---|---|
White blood cell, per μL | 10 000 ± 2 800 | 9 000 ± 2 500 |
Absolute lymphocyte count, per μL | 8 000 ± 1 600 | 7 000 ± 1 900 |
Absolute neutrophil count, per μL | 1 500 ± 300 | 1 400 ± 400 |
Absolute monocyte count, per μL | 600 ± 100 | 700 ± 200 |
Red blood cell, × 103/μL | 3 000 ± 100 | 3 000 ± 400 |
Hematocrit, % | 52 ± 3 | 51±7 |
Sample sizes consisted of 6 mice per group, analyzed between 6 to 8 weeks of age. Red and white blood cell counts were determined using a Coulter counter. Hematocrits were obtained by manually scoring microcapillary tubes following centrifugation. Differential counts were determined by manually scoring blood smears. No significant differences were observed between wild-type and Gab2−/− mice for any hematologic parameter. All values except hematocrit were rounded to the nearest 100.