Table 3 Patient characteristics... | American Society of Hematology

Table 3

Patient characteristics according to number of nonpermissive mismatches

Group	Total	Full match	Zero nonpermissive mismatch	One nonpermissive mismatch	Two or more nonpermissive mismatches
Total	4050	712	2670	602	66
Patient age, median y	30	32	30	29	29
Sex, donor/patient, no. patients
Male/male	1673	312	1096	237	28
Male/female	785	134	518	119	14
Female/male	769	115	524	117	13
Female/female	823	151	532	129	11
Disease, no. patients
ALL	981	162	668	139	12
ANLL	1075	196	698	158	23
CML	703	119	453	115	16
Hereditary disease	85	14	56	15	0
MDS	476	91	304	72	9
Malignant lymnphoma	349	69	229	48	3
Multiple myeloma	42	8	29	4	1
Severe aplastic anemia	247	33	175	37	2
Other disease	92	20	58	14	0
*Risk of leukemia relapse, no. patients**
Standard risk	1308	249	857	181	21
High risk	1451	228	962	231	30
Diseases other than leukemia	1291	235	851	190	15
GVHD prophylaxis, no. patients
Cyclosporin-based	2198	402	1444	319	33
Tacrolimus-based	1852	310	1226	283	33
ATG, no. patients
ATG	323	48	215	53	7
Non-ATG	3727	664	2455	549	59
Preconditioning, no. patients
TBI regimen	3117	539	2071	449	58
Non-TBI regimen	933	173	599	153	8

Group	Total	Full match	Zero nonpermissive mismatch	One nonpermissive mismatch	Two or more nonpermissive mismatches
Total	4050	712	2670	602	66
Patient age, median y	30	32	30	29	29
Sex, donor/patient, no. patients
Male/male	1673	312	1096	237	28
Male/female	785	134	518	119	14
Female/male	769	115	524	117	13
Female/female	823	151	532	129	11
Disease, no. patients
ALL	981	162	668	139	12
ANLL	1075	196	698	158	23
CML	703	119	453	115	16
Hereditary disease	85	14	56	15	0
MDS	476	91	304	72	9
Malignant lymnphoma	349	69	229	48	3
Multiple myeloma	42	8	29	4	1
Severe aplastic anemia	247	33	175	37	2
Other disease	92	20	58	14	0
*Risk of leukemia relapse, no. patients**
Standard risk	1308	249	857	181	21
High risk	1451	228	962	231	30
Diseases other than leukemia	1291	235	851	190	15
GVHD prophylaxis, no. patients
Cyclosporin-based	2198	402	1444	319	33
Tacrolimus-based	1852	310	1226	283	33
ATG, no. patients
ATG	323	48	215	53	7
Non-ATG	3727	664	2455	549	59
Preconditioning, no. patients
TBI regimen	3117	539	2071	449	58
Non-TBI regimen	933	173	599	153	8

ALL indicates acute lymphoblastic leukemia; ANLL, acute non-lymphoblastic leukemia; CML, chronic myeloid leukemia; MDS, myelodysplastic syndrome; and TBI, total body irradiation.

Standard risk for leukemia relapse was defined as the status of the 1st CR of AML and ALL and the 1st CP of CML at transplant, while high risk was defined as a more advanced status than standard risk in AML, ALL, and CML, and diseases other than leukemia was defined as other than ALL, ANLL, and CML.

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