Table 2 CFU frequency for sorted... | American Society of Hematology

Table 2

CFU frequency for sorted subpopulations

Cells and fraction	CFU/5000 cells
Naive BM
Total MNCs	10 ± 2
Lin⁻	101 ± 30
Lin⁻/Kit⁺/Sca⁻	256 ± 60
Lin⁻/Kit⁺/Sca⁺	1800 ± 372
CML BM, GFP⁺
Total MNCs	9 ± 3
Lin⁻	69 ± 19
Lin⁻/Kit⁺/Sca⁻	104 ± 37
Lin⁻/Kit⁺/Sca⁺	1743 ± 314
bcCML BM, GFP⁺/YFP⁺
Lin⁺	20 ± 5
Lin⁻/Sca⁻/CD150⁺	1575 ± 525
Lin⁻/Sca⁻/CD150⁻	3300 ± 1100
Lin⁻/Flt3⁻/Fc⁻low/CD150⁺	1750 ± 585
Lin⁻/Flt3⁻/Fc⁻low/CD150⁻	2210 ± 735
Lin⁻/Sca⁺/Flt⁺/CD150⁻	2395 ± 800

Cells and fraction	CFU/5000 cells
Naive BM
Total MNCs	10 ± 2
Lin⁻	101 ± 30
Lin⁻/Kit⁺/Sca⁻	256 ± 60
Lin⁻/Kit⁺/Sca⁺	1800 ± 372
CML BM, GFP⁺
Total MNCs	9 ± 3
Lin⁻	69 ± 19
Lin⁻/Kit⁺/Sca⁻	104 ± 37
Lin⁻/Kit⁺/Sca⁺	1743 ± 314
bcCML BM, GFP⁺/YFP⁺
Lin⁺	20 ± 5
Lin⁻/Sca⁻/CD150⁺	1575 ± 525
Lin⁻/Sca⁻/CD150⁻	3300 ± 1100
Lin⁻/Flt3⁻/Fc⁻low/CD150⁺	1750 ± 585
Lin⁻/Flt3⁻/Fc⁻low/CD150⁻	2210 ± 735
Lin⁻/Sca⁺/Flt⁺/CD150⁻	2395 ± 800

CFU/5000 indicates no. of colony-forming units (± standard deviation) normalized to 5000 cells; naive BM, bone marrow from naive control animals; MNCs, mononuclear cells; CML BM, bone marrow from animals bearing BCR/ABL-transduced cells; and bcCML BM, bone marrow from animals bearing BCR/ABL + Nup98/HoxA9–transduced cells.

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