Table 4

Clinical responses

VPA doseNo.CRCRpBM responseOverall no. response (%)No. courses to response (range)
50 mg/kg 40 10 19 (47) 1 (1-3) 
62.5 mg/kg 1 (14) 
75 mg/kg 2 (33) 
Total 53 12 22 (42) 1 (1-3) 
Previously untreated 33 11 17 (52) 1 (1-3) 
Previously treated 20 5 (25) 1 (1-2) 
VPA doseNo.CRCRpBM responseOverall no. response (%)No. courses to response (range)
50 mg/kg 40 10 19 (47) 1 (1-3) 
62.5 mg/kg 1 (14) 
75 mg/kg 2 (33) 
Total 53 12 22 (42) 1 (1-3) 
Previously untreated 33 11 17 (52) 1 (1-3) 
Previously treated 20 5 (25) 1 (1-2) 
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