Successful/available karyotype results among the 3 TLX1-defined groups
. | TLX1-high, no. (%) . | TLX1-low, no. (%) . | TLX1-neg, no. (%) . |
---|---|---|---|
Total, n = 264 | 35‡ (13) | 57§ (22) | 172¶ (65) |
Karyotypes available, n = 175* | 28 (16) | 42 (24) | 105 (60) |
Abnormal (10)(q24)† | 11/28 (39) | 0 | 0 |
Abnormal (clonal) with normal (10)(q24) | 8/28 (29) | 31/42 (74) | 65/105 (62) |
46XX or 46XY | 9/28 (32) | 11/42 (26) | 40/105 (38) |
. | TLX1-high, no. (%) . | TLX1-low, no. (%) . | TLX1-neg, no. (%) . |
---|---|---|---|
Total, n = 264 | 35‡ (13) | 57§ (22) | 172¶ (65) |
Karyotypes available, n = 175* | 28 (16) | 42 (24) | 105 (60) |
Abnormal (10)(q24)† | 11/28 (39) | 0 | 0 |
Abnormal (clonal) with normal (10)(q24) | 8/28 (29) | 31/42 (74) | 65/105 (62) |
46XX or 46XY | 9/28 (32) | 11/42 (26) | 40/105 (38) |
Unavailable karyotypes include 1, 4, and 17 failed karyotype attempts among the TLX1-high, TLX1-low, and TLX1-neg groups, respectively.
(10)(q24) aberrations included t(10;14)(q24;q11) in 7 cases, t(7;10)(q35;q24) in 2 cases, and del(10)(q24) and der(10) for 1 case each.
Thirty adults and 5 children.
Forty-one adults and 16 children.
One hundred adults and 72 children.