Table 1 The Wdr1 gt allele is homozygous... | American Society of Hematology

Table 1

The Wdr1^gt allele is homozygous lethal

Age ofembryos*	Number and genotype of embryos†			P‡
Age ofembryos*	Wdr1^+/+	Wdr1^+/gt	Wdr1^gt/gt	P‡
Weaning
Expected	16	32	16	—
Observed	24	40	0	< .001
E10.5
Expected	7	14	7	—
Observed	13	16	0	.004
E6.5
Expected	9	18	9	—
Observed	14	21	2	.024
E3.5
Expected	13	26	13	—
Observed	15	27	8	.33

Age ofembryos*	Number and genotype of embryos†			P‡
Age ofembryos*	Wdr1^+/+	Wdr1^+/gt	Wdr1^gt/gt	P‡
Weaning
Expected	16	32	16	—
Observed	24	40	0	< .001
E10.5
Expected	7	14	7	—
Observed	13	16	0	.004
E6.5
Expected	9	18	9	—
Observed	14	21	2	.024
E3.5
Expected	13	26	13	—
Observed	15	27	8	.33

— indicates not applicable.

Days after conception at which morning of plug equals embryonic day 0.5.

Number and genotype of embryos from matings of Wdr1^+/gt parents.

Fischer exact testing using two-sided P values.