Correlation of FLT3-TKD mutations with cytogenetics in 3018 patients
| Cytogenetic subgroup . | Total, no. . | FLT TKDmut, no. . | FLT TKDmut, % . | P . |
|---|---|---|---|---|
| Normal | 1472 | 88 | 6.0 | .003 |
| t(15;17)/PML-RARA | 130 | 10 | 7.7 | .116 |
| t(8;21) | 88 | 2 | 2.3 | .260 |
| Trisomy 8 | 129 | 6 | 4.7 | .934 |
| 11q23/MLL | 109 | 7 | 6.4 | .421 |
| 5q-/-5 | 31 | 0 | 0.0 | .209 |
| 7q-/-7 | 60 | 1 | 1.7 | .251 |
| inv(16)/t(16;16) | 119 | 6 | 5.0 | .902 |
| inv(3)/t(3;3) | 44 | 2 | 4.5 | .936 |
| t(6;9)(p23;q34) | 6 | 0 | 0.0 | .582 |
| Complex aberrant | 430 | 4 | 0.9 | <.001 |
| Other aberrations | 406 | 19 | 4.7 | .900 |
| Total | 3018 | 145 | 4.8 | — |
| Cytogenetic subgroup . | Total, no. . | FLT TKDmut, no. . | FLT TKDmut, % . | P . |
|---|---|---|---|---|
| Normal | 1472 | 88 | 6.0 | .003 |
| t(15;17)/PML-RARA | 130 | 10 | 7.7 | .116 |
| t(8;21) | 88 | 2 | 2.3 | .260 |
| Trisomy 8 | 129 | 6 | 4.7 | .934 |
| 11q23/MLL | 109 | 7 | 6.4 | .421 |
| 5q-/-5 | 31 | 0 | 0.0 | .209 |
| 7q-/-7 | 60 | 1 | 1.7 | .251 |
| inv(16)/t(16;16) | 119 | 6 | 5.0 | .902 |
| inv(3)/t(3;3) | 44 | 2 | 4.5 | .936 |
| t(6;9)(p23;q34) | 6 | 0 | 0.0 | .582 |
| Complex aberrant | 430 | 4 | 0.9 | <.001 |
| Other aberrations | 406 | 19 | 4.7 | .900 |
| Total | 3018 | 145 | 4.8 | — |
— indicates not applicable.