Serum electrolyte levels as measured at diagnosis of CML and after imatinib mesylate or α-interferon therapy
Variable . | Treatment . | |||||||
---|---|---|---|---|---|---|---|---|
Imatinib (n = 17) . | P* . | α-interferon (n = 12) . | P* . | P† . | P‡ . | |||
Before . | After . | Before . | After . | |||||
Phosphate, mM | 1.04 ± 0.18 | 0.8 ± 0.13 | < .001 | 1.09 ± 1.03 | 1.03 ± 0.15 | .37 | .44 | .001 |
Total Ca2+, mM | 2.32 ± 0.11 | 2.20 ± 0.13 | < .001 | 2.30 ± 0.1 | 2.26 ± 0.1 | .20 | .59 | .23 |
Ionized Ca2+, mM | 1.18 ± 0.05 | 1.14 ± 0.05 | < .005 | 1.17 ± 0.04 | 1.14 ± 0.05 | .16 | .46 | .06 |
Variable . | Treatment . | |||||||
---|---|---|---|---|---|---|---|---|
Imatinib (n = 17) . | P* . | α-interferon (n = 12) . | P* . | P† . | P‡ . | |||
Before . | After . | Before . | After . | |||||
Phosphate, mM | 1.04 ± 0.18 | 0.8 ± 0.13 | < .001 | 1.09 ± 1.03 | 1.03 ± 0.15 | .37 | .44 | .001 |
Total Ca2+, mM | 2.32 ± 0.11 | 2.20 ± 0.13 | < .001 | 2.30 ± 0.1 | 2.26 ± 0.1 | .20 | .59 | .23 |
Ionized Ca2+, mM | 1.18 ± 0.05 | 1.14 ± 0.05 | < .005 | 1.17 ± 0.04 | 1.14 ± 0.05 | .16 | .46 | .06 |
Values shown are means plus or minus standard deviations.
P values for the comparison of paired data (before and after) using paired t test.
P values describe the comparison of before-imatinib treatment data with before-α-interferon treatment data using the t test.
P values describe the comparison of after-imatinib treatment data with after-α-interferon treatment data using the t test.