Table 1 Clinical and laboratory... | American Society of Hematology

Table 1

Clinical and laboratory characteristics of the ET family

Characteristics	C1 Son	C2 Daughter	C3 Mother	C4 Father
Age (years)	6	9	33	34
Sex	Male	Female	Female	Male
Palpable splenomegaly	No	No	No	No
History of thrombosis	No	No	No	No
History of hemorrhage	No	No	No	No
WBC count (×10³/µL)	10.2	10.2	9.2	8.1
Hemoglobin (g/dL)	12.2	13.0	13.2	14.6
Platelet count (×10³/µL)	1027	568	493	275
Ferritin (ng/mL)	68	—	—	—
Erythrocyte sedimentation rate (mm/h)	6	2	—	—
Cytogenetics	46, XY	—	—	—
Peripheral blood BCR-ABL PCR	Negative	—	—	—
JAK2 mutations
V₆₁₇F	Negative	Negative	Negative	Negative
R₅₆₄Q	Positive	Positive	Positive	Negative
MPL mutations
W₅₁₅	Negative	—	—	—
S₅₀₅	Negative	—	—	—

Characteristics	C1 Son	C2 Daughter	C3 Mother	C4 Father
Age (years)	6	9	33	34
Sex	Male	Female	Female	Male
Palpable splenomegaly	No	No	No	No
History of thrombosis	No	No	No	No
History of hemorrhage	No	No	No	No
WBC count (×10³/µL)	10.2	10.2	9.2	8.1
Hemoglobin (g/dL)	12.2	13.0	13.2	14.6
Platelet count (×10³/µL)	1027	568	493	275
Ferritin (ng/mL)	68	—	—	—
Erythrocyte sedimentation rate (mm/h)	6	2	—	—
Cytogenetics	46, XY	—	—	—
Peripheral blood BCR-ABL PCR	Negative	—	—	—
JAK2 mutations
V₆₁₇F	Negative	Negative	Negative	Negative
R₅₆₄Q	Positive	Positive	Positive	Negative
MPL mutations
W₅₁₅	Negative	—	—	—
S₅₀₅	Negative	—	—	—