Hematologic and nonhematologic toxicity
| Toxicity . | Grade . | |||||
|---|---|---|---|---|---|---|
| 1-2 . | 3 . | 4 . | ||||
| No. . | % . | No. . | % . | No. . | % . | |
| Hematologic | ||||||
| Anemia | 12 | 15 | 2 | 3 | ||
| Leucopenia | 13 | 16 | 1 | 1 | ||
| Thrombocytopenia | 25 | 32 | 5 | 6 | ||
| Nonhematologic | ||||||
| Infection/sepsis | 34 | 43 | 13 | 16 | 3/2* | 4/3* |
| Herpes zoster | 3 | 4 | 3 | 4 | — | |
| Diarrhea | 17 | 22 | 6 | 8 | — | |
| Constipation | 21 | 27 | 3 | 4 | — | |
| Nausea, emesis | 26 | 33 | 1 | 1 | — | |
| Polyneuropathy | 39 | 49 | 4 | 5 | 1 | 1 |
| Exanthema | 6 | 8 | — | 1 | 1 | |
| Insomnia/fatigue | 32 | 40 | 2 | 3 | — | |
| Toxicity . | Grade . | |||||
|---|---|---|---|---|---|---|
| 1-2 . | 3 . | 4 . | ||||
| No. . | % . | No. . | % . | No. . | % . | |
| Hematologic | ||||||
| Anemia | 12 | 15 | 2 | 3 | ||
| Leucopenia | 13 | 16 | 1 | 1 | ||
| Thrombocytopenia | 25 | 32 | 5 | 6 | ||
| Nonhematologic | ||||||
| Infection/sepsis | 34 | 43 | 13 | 16 | 3/2* | 4/3* |
| Herpes zoster | 3 | 4 | 3 | 4 | — | |
| Diarrhea | 17 | 22 | 6 | 8 | — | |
| Constipation | 21 | 27 | 3 | 4 | — | |
| Nausea, emesis | 26 | 33 | 1 | 1 | — | |
| Polyneuropathy | 39 | 49 | 4 | 5 | 1 | 1 |
| Exanthema | 6 | 8 | — | 1 | 1 | |
| Insomnia/fatigue | 32 | 40 | 2 | 3 | — | |
Values for Grade 5.