Table 5.

Response after peripheral blood stem cell transplantation (PBSCT) (median follow-up 10.8 months).*

NResponse, %Stable, %Not Evaluated, %
* 1 died before evaluation and 1 too soon to evaluate 
One patient showed borderline worsening at 15 months, but at 24 months, patient reported substantial improvement; no repeat neuropathy impairment score was performed. 
2 complete responses, 3 very good partial response, and 1 minimal response 
This research was originally published in Blood.
Dispenzieri et al. POEMS Syndrome: Definitions and Long-term Outcome.
Blood
.
2003
;
101
:
2496
–2506
. © by the American Society of Hematology. 
Neurologic 16 87 … 13 
Subjective 16 87 … 13 
Nerve conduction studies (at 1 yr) 11 36 55 
Neuropathy impairment score 16 25 12 56 
Hematologic 16 56 37 
Non-secretory NA NA 100 
Immunofixation only 43 14 43 
Serum protein electrophoresis (SPEP) evaluable 100 … … 
Organ 11 82 … 18 
Hepatomegaly 60 … 40 
Splenomegaly 10 50 20 30 
Lymphadenopathy 71 29 
Extravascular volume overload 14 79 … 21 
Ascites 83 … 17 
Effusion 100 … … 
Edema 14 79 … 21 
Skin changes 13 54 15 31 
Papilledema 50 … 50 
Endocrine 13 23 69 
Pulmonary 15 20 … 80 
NResponse, %Stable, %Not Evaluated, %
* 1 died before evaluation and 1 too soon to evaluate 
One patient showed borderline worsening at 15 months, but at 24 months, patient reported substantial improvement; no repeat neuropathy impairment score was performed. 
2 complete responses, 3 very good partial response, and 1 minimal response 
This research was originally published in Blood.
Dispenzieri et al. POEMS Syndrome: Definitions and Long-term Outcome.
Blood
.
2003
;
101
:
2496
–2506
. © by the American Society of Hematology. 
Neurologic 16 87 … 13 
Subjective 16 87 … 13 
Nerve conduction studies (at 1 yr) 11 36 55 
Neuropathy impairment score 16 25 12 56 
Hematologic 16 56 37 
Non-secretory NA NA 100 
Immunofixation only 43 14 43 
Serum protein electrophoresis (SPEP) evaluable 100 … … 
Organ 11 82 … 18 
Hepatomegaly 60 … 40 
Splenomegaly 10 50 20 30 
Lymphadenopathy 71 29 
Extravascular volume overload 14 79 … 21 
Ascites 83 … 17 
Effusion 100 … … 
Edema 14 79 … 21 
Skin changes 13 54 15 31 
Papilledema 50 … 50 
Endocrine 13 23 69 
Pulmonary 15 20 … 80 
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