Evaluation of patients with suspected drug-induced thrombocytopenia.
Determine the probability for a causal relation of the suspected drug to the occurrence of thrombocytopenia using the clinical criteria presented in Table 1.
Determine previously published experience. Check the DITP database (www.ouhsc.edu/platelets) for previously published reports describing the suspected drug. Are there previous reports with definite or probable evidence for a causal relation of the suspected drug and thrombocytopenia?
Determine the presence of drug-dependent anti-platelet antibodies to confirm the etiologic role of the drug that is suspected as the cause of thrombocytopenia.
If the drug is confirmed as the cause of thrombocytopenia by clinical criteria and/or by demonstration of drug-dependent anti-platelet antibodies, report the patient to the FDA Adverse Event Reporting System by using www.fda.gov/medwatch/.
If there are no or few published case reports with definite or probable clinical evidence for a causal role of the drug with thrombocytopenia, publish your experience.
Determine the probability for a causal relation of the suspected drug to the occurrence of thrombocytopenia using the clinical criteria presented in Table 1.
Determine previously published experience. Check the DITP database (www.ouhsc.edu/platelets) for previously published reports describing the suspected drug. Are there previous reports with definite or probable evidence for a causal relation of the suspected drug and thrombocytopenia?
Determine the presence of drug-dependent anti-platelet antibodies to confirm the etiologic role of the drug that is suspected as the cause of thrombocytopenia.
If the drug is confirmed as the cause of thrombocytopenia by clinical criteria and/or by demonstration of drug-dependent anti-platelet antibodies, report the patient to the FDA Adverse Event Reporting System by using www.fda.gov/medwatch/.
If there are no or few published case reports with definite or probable clinical evidence for a causal role of the drug with thrombocytopenia, publish your experience.