Table 1. Integrative therapies that have... | American Society of Hematology

Table 1.

Integrative therapies that have been investigated for use as a supportive care therapy in children with hematological malignancies (reviewed in Ladas et al¹⁰ and Myers et al¹¹).

Symptom	Alternative medical systems	Mind-body medicine	Biologically based therapies	Manipulative and body-based methods	Energy therapies
*Randomized controlled trial
(+) Positive results observed
(−) Negative results observed
ns indicates not studied.
Nausea/vomiting	Acupressure (−)	Cognitive Distraction* (+)  Hypnosis* (+)  Music* (+)	Massage (−)	ns	ns
Mucositis	Homeopathic mouth rinse* (+/−)	ns	Glutamine* (+)	ns	ns
Pain	ns	ns	ns	Massage* (−)	ns
Procedural pain	ns	Music (+)  Hypnosis* (+)  Art (+)	ns	ns	ns
Fatigue	ns	ns	ns	Massage* (−)	ns
Cachexia	ns	ns	Fish oil* (+)	ns	ns
Anxiety/Insomnia	ns	Hypnosis* (+)	ns	Massage* (+)	ns
Weight gain	ns	ns	Creatine (+)	ns	ns
Constipation	ns	ns	ns	ns	ns
Hepatotoxicity	ns	ns	Milk thistle* (+)	ns	ns
Mood	ns	ns	ns	Massage* (+)	ns

Symptom	Alternative medical systems	Mind-body medicine	Biologically based therapies	Manipulative and body-based methods	Energy therapies
*Randomized controlled trial
(+) Positive results observed
(−) Negative results observed
ns indicates not studied.
Nausea/vomiting	Acupressure (−)	Cognitive Distraction* (+)  Hypnosis* (+)  Music* (+)	Massage (−)	ns	ns
Mucositis	Homeopathic mouth rinse* (+/−)	ns	Glutamine* (+)	ns	ns
Pain	ns	ns	ns	Massage* (−)	ns
Procedural pain	ns	Music (+)  Hypnosis* (+)  Art (+)	ns	ns	ns
Fatigue	ns	ns	ns	Massage* (−)	ns
Cachexia	ns	ns	Fish oil* (+)	ns	ns
Anxiety/Insomnia	ns	Hypnosis* (+)	ns	Massage* (+)	ns
Weight gain	ns	ns	Creatine (+)	ns	ns
Constipation	ns	ns	ns	ns	ns
Hepatotoxicity	ns	ns	Milk thistle* (+)	ns	ns
Mood	ns	ns	ns	Massage* (+)	ns