Names and characteristics of commercial superparamagnetic iron oxide (SPIO) agents.
| Classification . | Agent . | US adopted name . | Trade name . | Coating material . | Hydrodynamic diameter . |
|---|---|---|---|---|---|
| AMI-121, AMI-25, AMI-227, and Code 7228 are distributed by AMAG Pharmaceuticals/Guerbet; OMP and NC100150 are distributed by GE-Healthcare; SHU-555A and SHU-555C are distributed by Schering; VSOP-C184 is distributed by Ferropharm. | |||||
| Table is modified from Wang et al, 200140 and Corot et al, 2006.8 | |||||
| Oral SPIO | AMI-121 | Ferumoxsil | Lumirem, Gastromark | Silicon | 300 nm |
| OMP | Ferristene | Abdoscan | Sulphonated styrene-divinylbenzene | 3.5 μm | |
| SSPIO | AMI-25 | Ferumoxide | Endorem, Feridex IV | Dextran | 80–180 nm |
| SHU-555A | Ferucarbotran or Ferrixan | Resovist, Cliavist | Carboxydextran | 60–62 nm | |
| USPIO | VSOP-C184 | Citrate | 7 nm | ||
| NC100150 | Feruglose | Clariscan | Pegylated Starch | 20 nm | |
| SHU-555C | Supravist | Carboxydextran | 21 nm | ||
| Code 7228 | Ferumoxytol | Carboxymethyl Dextran | 30 nm | ||
| AMI-227 | Ferumoxtran-10 | Sinerem, Combidex | Dextran | 15–40 nm | |
| Classification . | Agent . | US adopted name . | Trade name . | Coating material . | Hydrodynamic diameter . |
|---|---|---|---|---|---|
| AMI-121, AMI-25, AMI-227, and Code 7228 are distributed by AMAG Pharmaceuticals/Guerbet; OMP and NC100150 are distributed by GE-Healthcare; SHU-555A and SHU-555C are distributed by Schering; VSOP-C184 is distributed by Ferropharm. | |||||
| Table is modified from Wang et al, 200140 and Corot et al, 2006.8 | |||||
| Oral SPIO | AMI-121 | Ferumoxsil | Lumirem, Gastromark | Silicon | 300 nm |
| OMP | Ferristene | Abdoscan | Sulphonated styrene-divinylbenzene | 3.5 μm | |
| SSPIO | AMI-25 | Ferumoxide | Endorem, Feridex IV | Dextran | 80–180 nm |
| SHU-555A | Ferucarbotran or Ferrixan | Resovist, Cliavist | Carboxydextran | 60–62 nm | |
| USPIO | VSOP-C184 | Citrate | 7 nm | ||
| NC100150 | Feruglose | Clariscan | Pegylated Starch | 20 nm | |
| SHU-555C | Supravist | Carboxydextran | 21 nm | ||
| Code 7228 | Ferumoxytol | Carboxymethyl Dextran | 30 nm | ||
| AMI-227 | Ferumoxtran-10 | Sinerem, Combidex | Dextran | 15–40 nm | |