Table 3.

Tests used for diagnosis of the antiphospholipid syndrome.

Immunoassays 
    Biologic false-positive serologic test for syphilis Anticardiolipin antibodies (cofactor-dependent assay) Anti-β2GPI antibodies Antiphosphatidylserine antibodies Antiprothrombin antibodies 
Coagulation Tests 
    Dilute Russell viper venom time (DRVVT) with confirmatory tests 
aPTT:

  • —evidence of inhibitor with mixing studies

  • —panel of aPL-sensitive and insensitive aPTT reagents

  • —platelet neutralization procedure

 
    Kaolin clotting time 
    Tissue thromboplastin inhibition test 
    Hexagonal phase array test 
    Textarin/ecarin test 
Immunoassays 
    Biologic false-positive serologic test for syphilis Anticardiolipin antibodies (cofactor-dependent assay) Anti-β2GPI antibodies Antiphosphatidylserine antibodies Antiprothrombin antibodies 
Coagulation Tests 
    Dilute Russell viper venom time (DRVVT) with confirmatory tests 
aPTT:

  • —evidence of inhibitor with mixing studies

  • —panel of aPL-sensitive and insensitive aPTT reagents

  • —platelet neutralization procedure

 
    Kaolin clotting time 
    Tissue thromboplastin inhibition test 
    Hexagonal phase array test 
    Textarin/ecarin test 
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