AEs experienced during acalabrutinib treatment (≥15% any grade) for all treated patients (N = 33)
| AE . | n (%) . | ||||
|---|---|---|---|---|---|
| Any grade . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | |
| Diarrhea | 19 (58) | 15 (45) | 4 (12) | 0 | 0 |
| Headache | 13 (39) | 9 (27) | 4 (12) | 0 | 0 |
| Cough | 11 (33) | 6 (18) | 5 (15) | 0 | 0 |
| Weight increased | 10 (30) | 6 (18) | 3 (9) | 1 (3) | 0 |
| Nausea | 9 (27) | 6 (18) | 2 (6) | 1 (3) | 0 |
| Contusion | 8 (24) | 5 (15) | 3 (9) | 0 | 0 |
| Upper respiratory tract infection | 8 (24) | 2 (6) | 5 (15) | 1 (3) | 0 |
| Arthralgia | 7 (21) | 6 (18) | 1 (3) | 0 | 0 |
| Pyrexia | 7 (21) | 5 (15) | 1 (3) | 1 (3) | 0 |
| Vomiting | 7 (21) | 5 (15) | 2 (6) | 0 | 0 |
| Fatigue | 6 (18) | 3 (9) | 3 (9) | 0 | 0 |
| Myalgia | 6 (18) | 2 (6) | 3 (9) | 0 | 0 |
| Rash | 6 (18) | 5 (15) | 1 (3) | 0 | 0 |
| Constipation | 5 (15) | 4 (12) | 1 (3) | 0 | 0 |
| Dizziness | 5 (15) | 3 (9) | 2 (6) | 0 | 0 |
| Ecchymosis | 5 (15) | 4 (12) | 1 (3) | 0 | 0 |
| Fall | 5 (15) | 3 (9) | 2 (6) | 0 | 0 |
| Noncardiac chest pain | 5 (15) | 3 (9) | 1 (3) | 1 (3) | 0 |
| AE . | n (%) . | ||||
|---|---|---|---|---|---|
| Any grade . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | |
| Diarrhea | 19 (58) | 15 (45) | 4 (12) | 0 | 0 |
| Headache | 13 (39) | 9 (27) | 4 (12) | 0 | 0 |
| Cough | 11 (33) | 6 (18) | 5 (15) | 0 | 0 |
| Weight increased | 10 (30) | 6 (18) | 3 (9) | 1 (3) | 0 |
| Nausea | 9 (27) | 6 (18) | 2 (6) | 1 (3) | 0 |
| Contusion | 8 (24) | 5 (15) | 3 (9) | 0 | 0 |
| Upper respiratory tract infection | 8 (24) | 2 (6) | 5 (15) | 1 (3) | 0 |
| Arthralgia | 7 (21) | 6 (18) | 1 (3) | 0 | 0 |
| Pyrexia | 7 (21) | 5 (15) | 1 (3) | 1 (3) | 0 |
| Vomiting | 7 (21) | 5 (15) | 2 (6) | 0 | 0 |
| Fatigue | 6 (18) | 3 (9) | 3 (9) | 0 | 0 |
| Myalgia | 6 (18) | 2 (6) | 3 (9) | 0 | 0 |
| Rash | 6 (18) | 5 (15) | 1 (3) | 0 | 0 |
| Constipation | 5 (15) | 4 (12) | 1 (3) | 0 | 0 |
| Dizziness | 5 (15) | 3 (9) | 2 (6) | 0 | 0 |
| Ecchymosis | 5 (15) | 4 (12) | 1 (3) | 0 | 0 |
| Fall | 5 (15) | 3 (9) | 2 (6) | 0 | 0 |
| Noncardiac chest pain | 5 (15) | 3 (9) | 1 (3) | 1 (3) | 0 |