Patient and disease characteristics
| Characteristic . | All patients (N = 71) . | RT only (n = 36) . | Combined therapy (n = 29) . | RT-only vs combined therapy, P . | Systemic therapy only (n = 6) . |
|---|---|---|---|---|---|
| Age | |||||
| Median (range), y | 39 (18-73) | 38 (18-69) | 40 (22-73) | 49 (31-68) | |
| ≥45 y | 30 (42) | 15 (42) | 11 (38) | .803 | 4 (67) |
| Male | 53 (75) | 26 (72) | 23 (79) | .573 | 4 (67) |
| Disease stage | |||||
| I | 28 (39) | 22 (61) | 6 (21) | .001 | 0 |
| II | 43 (61) | 14 (39) | 23 (79) | 6 (100) | |
| Disease location | |||||
| Above diaphragm | 56 (79) | 32 (89) | 21 (72) | .114 | 3 (50) |
| Below diaphragm | 15 (21) | 4 (11) | 8 (28) | 3 (50) | |
| Mediastinal involvement | 3 (4) | 2 (6) | 1 (3) | 1.00 | 0 |
| ECOG PS | |||||
| 0 | 64 (90) | 33 (92) | 27 (93) | 1.00 | 4 (67) |
| 1 | 7 (10) | 3 (8) | 2 (7) | 2 (33) | |
| B symptoms | 5 (7) | 0 | 4 (14) | .035 | 1 (17) |
| Extranodal disease | 4 (7) | 1 (3) | 3 (10) | .316 | 0 |
| Histologic pattern | |||||
| Typical | 48 (68) | 28 (78) | 17 (59) | .113 | 3 (50) |
| Variant | 23 (32) | 8 (22) | 12 (41) | 3 (50) | |
| PET-CT imaging | 60 (85) | 29 (81) | 25 (86) | .742 | 6 (100) |
| Tumor size* | |||||
| Median (range), cm | 3.0 (1.2-8.5) | 3.0 (1.4-6.9) | 3.3 (1.2-8.5) | 2.8 (1.2-3.0) | |
| ≥5 cm | 8 (11) | 3 (8) | 5 (18) | .282 | 0 |
| Characteristic . | All patients (N = 71) . | RT only (n = 36) . | Combined therapy (n = 29) . | RT-only vs combined therapy, P . | Systemic therapy only (n = 6) . |
|---|---|---|---|---|---|
| Age | |||||
| Median (range), y | 39 (18-73) | 38 (18-69) | 40 (22-73) | 49 (31-68) | |
| ≥45 y | 30 (42) | 15 (42) | 11 (38) | .803 | 4 (67) |
| Male | 53 (75) | 26 (72) | 23 (79) | .573 | 4 (67) |
| Disease stage | |||||
| I | 28 (39) | 22 (61) | 6 (21) | .001 | 0 |
| II | 43 (61) | 14 (39) | 23 (79) | 6 (100) | |
| Disease location | |||||
| Above diaphragm | 56 (79) | 32 (89) | 21 (72) | .114 | 3 (50) |
| Below diaphragm | 15 (21) | 4 (11) | 8 (28) | 3 (50) | |
| Mediastinal involvement | 3 (4) | 2 (6) | 1 (3) | 1.00 | 0 |
| ECOG PS | |||||
| 0 | 64 (90) | 33 (92) | 27 (93) | 1.00 | 4 (67) |
| 1 | 7 (10) | 3 (8) | 2 (7) | 2 (33) | |
| B symptoms | 5 (7) | 0 | 4 (14) | .035 | 1 (17) |
| Extranodal disease | 4 (7) | 1 (3) | 3 (10) | .316 | 0 |
| Histologic pattern | |||||
| Typical | 48 (68) | 28 (78) | 17 (59) | .113 | 3 (50) |
| Variant | 23 (32) | 8 (22) | 12 (41) | 3 (50) | |
| PET-CT imaging | 60 (85) | 29 (81) | 25 (86) | .742 | 6 (100) |
| Tumor size* | |||||
| Median (range), cm | 3.0 (1.2-8.5) | 3.0 (1.4-6.9) | 3.3 (1.2-8.5) | 2.8 (1.2-3.0) | |
| ≥5 cm | 8 (11) | 3 (8) | 5 (18) | .282 | 0 |
Unless otherwise noted, all data are n (%).
ECOG PS, Eastern Cooperative Oncology Group Performance Status score.
Tumor size was unavailable for 1 patient.