Table 2.

Univariate analysis

CharacteristicPFSOS
HR (95% CI)PHR (95% CI)P
Age 1.01 (0.98-1.04) .425 1.05 (0.99-1.11) .107 
Male 3.73 (0.86-16.30) .080 1.65 (0.19-14.20) .648 
Stage II 1.26 (0.45-3.53) .665 2.4 (0.28-20.65) .425 
ECOG PS 1 1.04 (0.30-3.62) .951 0.04 (0.00-265.72) .461 
Supradiaphragmatic disease 3.49 (0.80-15.24) .097 31.38 (0.01-85 218.00) .393 
B symptoms 0.63 (0.08-4.80) .630 0.05 (0.00-82 523.70) .673 
Extranodal disease 0.64 (0.08-4.90) .670 2.79 (0.32-24.07) .351 
Variant histologic pattern 0.65 (0.24-1.82) .417 0.39 (0.05-3.33) .39 
PET-CT imaging not performed 3.16 (1.24-8.04) .016 4.38 (0.74-25.88) .104 
Tumor size ≥5 cm 0.95 (0.27-3.34) .931 0.89 (0.10-7.65) .913 
Era of therapy     
 Before 2000*     
 2000-2010 0.55 (0.20-1.50) .240 0.38 (0.08-1.97) .251 
 2011-2017 0.24 (0.03-2.22) .210 <0.01 (0.00-1.6 × 10172.957 
CharacteristicPFSOS
HR (95% CI)PHR (95% CI)P
Age 1.01 (0.98-1.04) .425 1.05 (0.99-1.11) .107 
Male 3.73 (0.86-16.30) .080 1.65 (0.19-14.20) .648 
Stage II 1.26 (0.45-3.53) .665 2.4 (0.28-20.65) .425 
ECOG PS 1 1.04 (0.30-3.62) .951 0.04 (0.00-265.72) .461 
Supradiaphragmatic disease 3.49 (0.80-15.24) .097 31.38 (0.01-85 218.00) .393 
B symptoms 0.63 (0.08-4.80) .630 0.05 (0.00-82 523.70) .673 
Extranodal disease 0.64 (0.08-4.90) .670 2.79 (0.32-24.07) .351 
Variant histologic pattern 0.65 (0.24-1.82) .417 0.39 (0.05-3.33) .39 
PET-CT imaging not performed 3.16 (1.24-8.04) .016 4.38 (0.74-25.88) .104 
Tumor size ≥5 cm 0.95 (0.27-3.34) .931 0.89 (0.10-7.65) .913 
Era of therapy     
 Before 2000*     
 2000-2010 0.55 (0.20-1.50) .240 0.38 (0.08-1.97) .251 
 2011-2017 0.24 (0.03-2.22) .210 <0.01 (0.00-1.6 × 10172.957 

HR, hazard ratio.

*

The reference category is treatment before 2000.

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