Table 1.

WHO 2008 classification of mature T/NK-cell neoplasms.2 

* designates provisional entities 
Leukemic or disseminated 
    T-cell prolymphocytic leukemia 
    T-cell large granular lymphocytic leukemia 
    Chronic lymphoproliferative disorders of NK cells* 
    Aggressive NK-cell leukemia 
    Adult T-cell lymphoma/leukemia (HTLV1-positive) 
    Systemic Epstein-Barr virus (EBV)–positive T-cell lymphoproliferative disorders of childhood 
Extranodal 
    Extranodal NK/T-cell lymphoma, nasal type 
    Enteropathy-associated T-cell lymphoma 
    Hepatosplenic T-cell lymphoma 
Extranodal—cutaneous 
    Mycosis fungoides 
    Sézary syndrome 
    Primary cutaneous CD30+ lymphoproliferative disorders 
        Primary cutaneous anaplastic large cell lymphoma 
        Lymphomatoid papulosis 
    Subcutaneous panniculitis-like T-cell lymphoma 
    Primary cutaneous γδ T-cell lymphoma* 
    Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma* 
    Primary cutaneous small/medium CD4+ T-cell lymphoma* 
Nodal 
    Angioimmunoblastic T-cell lymphoma 
    Anaplastic large cell lymphoma, ALK-positive 
    Anaplastic large cell lymphoma, ALK-negative* 
    Peripheral T-cell lymphoma, not otherwise specified 
* designates provisional entities 
Leukemic or disseminated 
    T-cell prolymphocytic leukemia 
    T-cell large granular lymphocytic leukemia 
    Chronic lymphoproliferative disorders of NK cells* 
    Aggressive NK-cell leukemia 
    Adult T-cell lymphoma/leukemia (HTLV1-positive) 
    Systemic Epstein-Barr virus (EBV)–positive T-cell lymphoproliferative disorders of childhood 
Extranodal 
    Extranodal NK/T-cell lymphoma, nasal type 
    Enteropathy-associated T-cell lymphoma 
    Hepatosplenic T-cell lymphoma 
Extranodal—cutaneous 
    Mycosis fungoides 
    Sézary syndrome 
    Primary cutaneous CD30+ lymphoproliferative disorders 
        Primary cutaneous anaplastic large cell lymphoma 
        Lymphomatoid papulosis 
    Subcutaneous panniculitis-like T-cell lymphoma 
    Primary cutaneous γδ T-cell lymphoma* 
    Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma* 
    Primary cutaneous small/medium CD4+ T-cell lymphoma* 
Nodal 
    Angioimmunoblastic T-cell lymphoma 
    Anaplastic large cell lymphoma, ALK-positive 
    Anaplastic large cell lymphoma, ALK-negative* 
    Peripheral T-cell lymphoma, not otherwise specified 
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