Comparison of intensive and non-intensive induction treatments (in the absence of maintenance therapy): results of randomized studies.
| . | Conventional CT + single ASCT . | Conventional CT + double ASCT . | Novel agents + ASCT . | Novel agents without ASCT . |
|---|---|---|---|---|
| Abbreviations: CT, computed tomography; ASCT, autologous stem cell transplantation; CR, complete response; VGPR, very good partial response | ||||
| References | Attal1,8 | Attal8 | Harousseau20 | Palumbo37 |
| Child2 | Cavo9 | Morgan16 | Facon38 | |
| Harousseau3 | Barlogie36 | Cavo31 | San Miguel43 | |
| CR rate, % | 20–40 | 30–45 | 35–55 | 15–35 |
| > VGPR rate, % | 35–45 | 45–55 | 60–80 | 35–45 |
| PFS, mo | median 25–30 | median 30–40 | ? | 24–28 |
| . | Conventional CT + single ASCT . | Conventional CT + double ASCT . | Novel agents + ASCT . | Novel agents without ASCT . |
|---|---|---|---|---|
| Abbreviations: CT, computed tomography; ASCT, autologous stem cell transplantation; CR, complete response; VGPR, very good partial response | ||||
| References | Attal1,8 | Attal8 | Harousseau20 | Palumbo37 |
| Child2 | Cavo9 | Morgan16 | Facon38 | |
| Harousseau3 | Barlogie36 | Cavo31 | San Miguel43 | |
| CR rate, % | 20–40 | 30–45 | 35–55 | 15–35 |
| > VGPR rate, % | 35–45 | 45–55 | 60–80 | 35–45 |
| PFS, mo | median 25–30 | median 30–40 | ? | 24–28 |