Table 1.

Potential benefits and risks of TA for PPH prevention

BenefitsRisks
Less postpartum blood loss Minor side effects: nausea, vomiting, headache, and skin reactions 
Fewer red cell units transfused Arterial thromboembolism 
Less use of additional uterotonics Venous thromboembolism 
Less need for postpartum parenteral iron infusions Acute kidney injury including renal cortical necrosis and risk of end-stage renal disease 
Shorter length of stay Seizures 
BenefitsRisks
Less postpartum blood loss Minor side effects: nausea, vomiting, headache, and skin reactions 
Fewer red cell units transfused Arterial thromboembolism 
Less use of additional uterotonics Venous thromboembolism 
Less need for postpartum parenteral iron infusions Acute kidney injury including renal cortical necrosis and risk of end-stage renal disease 
Shorter length of stay Seizures 
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