Incidence of bleeding adjusted for exposure
| Reference . | Median exposure (mo) . | Overall bleeding incidence* . | Major bleeding incidence* . | |||
|---|---|---|---|---|---|---|
| Ibrutinib . | Control . | Ibrutinib . | Control . | Ibrutinib . | Control . | |
| 15 | 8.4 | 5.3 | 63.0 | 27.6 | 1.4 | 3.5 |
| 1 | 17.4 | 7.1 | — | — | 3.0 | 3.8 |
| 3 | 14.4 | 3 | — | — | 8.4 | 25.9 |
| 6 | 14.7 | 12.8 | 25.1 | 13.6 | 3.1 | 1.7 |
| Reference . | Median exposure (mo) . | Overall bleeding incidence* . | Major bleeding incidence* . | |||
|---|---|---|---|---|---|---|
| Ibrutinib . | Control . | Ibrutinib . | Control . | Ibrutinib . | Control . | |
| 15 | 8.4 | 5.3 | 63.0 | 27.6 | 1.4 | 3.5 |
| 1 | 17.4 | 7.1 | — | — | 3.0 | 3.8 |
| 3 | 14.4 | 3 | — | — | 8.4 | 25.9 |
| 6 | 14.7 | 12.8 | 25.1 | 13.6 | 3.1 | 1.7 |
–, Not available.
Incidence is reported per 100 person-years of exposure.