Drug cessation by line of therapy
| Line of therapy . | No. patients ceased drug/no. on therapy (%) . | Median time to drug cessation (mo) (range 0.1-55 mo) . | Reason for drug cessation . |
|---|---|---|---|
| First | 9/51 (18) | 14.4 | Adverse events, n = 6 |
| Progression/treatment failure, n = 3 | |||
| Second | 59/125 (47) | 15.5 | Adverse events, n = 40 |
| Progression/treatment failure, n = 13 | |||
| Pregnancy, n = 1 | |||
| Good CML response, n = 1 | |||
| Death, n = 4 | |||
| Third | 11/36 (30) | 13.5 | Adverse events, n = 5 |
| Progression/treatment failure, n = 1 | |||
| Death, n = 5 |
| Line of therapy . | No. patients ceased drug/no. on therapy (%) . | Median time to drug cessation (mo) (range 0.1-55 mo) . | Reason for drug cessation . |
|---|---|---|---|
| First | 9/51 (18) | 14.4 | Adverse events, n = 6 |
| Progression/treatment failure, n = 3 | |||
| Second | 59/125 (47) | 15.5 | Adverse events, n = 40 |
| Progression/treatment failure, n = 13 | |||
| Pregnancy, n = 1 | |||
| Good CML response, n = 1 | |||
| Death, n = 4 | |||
| Third | 11/36 (30) | 13.5 | Adverse events, n = 5 |
| Progression/treatment failure, n = 1 | |||
| Death, n = 5 |