Prognostic factors that affected the OS (univariate analysis)
| Variables . | Comparative factor/reference factor . | Univariate relative risk (95% CI) . | P . |
|---|---|---|---|
| Infiltration of FOXP3-positive cells | High/low | 0.30 (0.12-0.84) | .0233* |
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 3.33 (1.31-8.31) | .0121* |
| IPI category† | H/HI | 7.73 (1.89-28.38) | .0063* |
| H/LI | 22.56 (4.46-129.07) | .0004* | |
| H/L | 25.89 (5.00-152.12) | .0002* | |
| H-HI/L-LI | 4.10 (1.47-13.13) | .0064* | |
| Subtype | Non-GCB/GCB | 4.16 (1.19-26.25) | .0224* |
| Ki67 index | ≥80%/<80% | 2.88 (1.01-3.29) | .0493* |
| Variables . | Comparative factor/reference factor . | Univariate relative risk (95% CI) . | P . |
|---|---|---|---|
| Infiltration of FOXP3-positive cells | High/low | 0.30 (0.12-0.84) | .0233* |
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 3.33 (1.31-8.31) | .0121* |
| IPI category† | H/HI | 7.73 (1.89-28.38) | .0063* |
| H/LI | 22.56 (4.46-129.07) | .0004* | |
| H/L | 25.89 (5.00-152.12) | .0002* | |
| H-HI/L-LI | 4.10 (1.47-13.13) | .0064* | |
| Subtype | Non-GCB/GCB | 4.16 (1.19-26.25) | .0224* |
| Ki67 index | ≥80%/<80% | 2.88 (1.01-3.29) | .0493* |
CI, confidence interval; H, high; HI, high-intermediate; L, low; LI, low-intermediate.
*P < .05.
†Representative results with a significant P value are shown among all combinations of each IPI category, and among the H-HI group and the L-LI group.