Prognostic factors that affected PFS (univariate analysis)
| Variables . | Comparative factor/reference factor . | Univariate relative risk (95% CI) . | P . |
|---|---|---|---|
| Infiltration of FOXP3-positive cells | High/low | N.D. | N.D. |
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 2.64 (1.99-5.61) | .0171* |
| IPI category† | H/LI | 7.56 (1.86-27.22) | .0067* |
| H/L | 14.02 (4.05-90.67) | .0005* | |
| HI/L | 5.45 (1.94-19.37) | .0008* | |
| H-HI/L-LI | 0.0013 (1.66-8.48) | .0013* | |
| Subtype | Non-GCB/GCB | 2.94 (1.22-8.73) | .0136* |
| Ki67 index | ≥80%/<80% | 2.56 (1.07-5.53) | .0355* |
| Variables . | Comparative factor/reference factor . | Univariate relative risk (95% CI) . | P . |
|---|---|---|---|
| Infiltration of FOXP3-positive cells | High/low | N.D. | N.D. |
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 2.64 (1.99-5.61) | .0171* |
| IPI category† | H/LI | 7.56 (1.86-27.22) | .0067* |
| H/L | 14.02 (4.05-90.67) | .0005* | |
| HI/L | 5.45 (1.94-19.37) | .0008* | |
| H-HI/L-LI | 0.0013 (1.66-8.48) | .0013* | |
| Subtype | Non-GCB/GCB | 2.94 (1.22-8.73) | .0136* |
| Ki67 index | ≥80%/<80% | 2.56 (1.07-5.53) | .0355* |
N.D., no detection. All other abbreviations are explained in Table 2.
*P < .05.
†Representative results with a significant P value are shown among all combinations of each IPI category, and among the H-HI group and the L-LI group.