Prognostic factors that affect OS and PFS (bivariate analysis of infiltration of FOXP3/CTLA-4 double-positive cells and IPI categories)
| Variables . | Comparative factor/reference factor . | Multivariate relative risk (95% CI) . | P . |
|---|---|---|---|
| Prognostic factors that affected OS: | |||
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 5.79 (2.06-16.58) | .0010* |
| IPI category† | H/HI | 8.21 (1.86-32.85) | .0071* |
| H/LI | 46.28 (7.55-342.77) | <.0001* | |
| H/L | 40.95 (6.92-285.28) | <.0001* | |
| HI/LI | 5.63(1.50-27.87) | .0091* | |
| HI/L | 4.98 (1.39-23.66) | .0122* | |
| Prognostic factors that affected PFS: | |||
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 3.51 (1.50-7.97) | .0042* |
| IPI category† | H/HI | 2.71 (0.70-8.76) | .1359* |
| H/LI | 8.03 (1.90-30.70) | .0064* | |
| H/L | 18.90 (3.93-92.62) | .0005* | |
| HI/LI | 2.95 (1.21-7.82) | .0167* | |
| HI/L | 6.96 (2.42-25.13) | .0002* | |
| Variables . | Comparative factor/reference factor . | Multivariate relative risk (95% CI) . | P . |
|---|---|---|---|
| Prognostic factors that affected OS: | |||
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 5.79 (2.06-16.58) | .0010* |
| IPI category† | H/HI | 8.21 (1.86-32.85) | .0071* |
| H/LI | 46.28 (7.55-342.77) | <.0001* | |
| H/L | 40.95 (6.92-285.28) | <.0001* | |
| HI/LI | 5.63(1.50-27.87) | .0091* | |
| HI/L | 4.98 (1.39-23.66) | .0122* | |
| Prognostic factors that affected PFS: | |||
| Infiltration of FOXP3/CTLA-4 double-positive cells | High/low | 3.51 (1.50-7.97) | .0042* |
| IPI category† | H/HI | 2.71 (0.70-8.76) | .1359* |
| H/LI | 8.03 (1.90-30.70) | .0064* | |
| H/L | 18.90 (3.93-92.62) | .0005* | |
| HI/LI | 2.95 (1.21-7.82) | .0167* | |
| HI/L | 6.96 (2.42-25.13) | .0002* | |
Abbreviations are explained in Table 2.
*P < .05.
†Representative results with a significant P value are shown among all combinations.