Table 4.

Effect of IBS PRT settings on platelet inventory and number of theoretical PRT products

ParameterTime period
123456
Length, d 21 12 14 20 40 30 
Collection configuration Original* (no PRT settings) PRT1 PRT2 PRT3 PRT4 Normal 
Number of donations 152 104 84 158 288 227 
Number of products 326* 187 155 272 540 469 
Overall split rate 2.14* 1.79 1.85 1.72 1.88 2.07 
Triple donations, % 46 48 30 30 33 32 
Double donations, % 42 45 56 50 53 61 
Single donations, % 12 14 20 14 
Products discarded 1* 40 44 
Discard rate, % N/A 13 
PRT products attempted from single and double collections N/A 101 106 190 347 293 
PRT units produced N/A 35 59 79 160 23 
PRT success rate, % N/A 35 56 42 46 
Overall PRT product inventory, % N/A 19 38 29 30 
ParameterTime period
123456
Length, d 21 12 14 20 40 30 
Collection configuration Original* (no PRT settings) PRT1 PRT2 PRT3 PRT4 Normal 
Number of donations 152 104 84 158 288 227 
Number of products 326* 187 155 272 540 469 
Overall split rate 2.14* 1.79 1.85 1.72 1.88 2.07 
Triple donations, % 46 48 30 30 33 32 
Double donations, % 42 45 56 50 53 61 
Single donations, % 12 14 20 14 
Products discarded 1* 40 44 
Discard rate, % N/A 13 
PRT products attempted from single and double collections N/A 101 106 190 347 293 
PRT units produced N/A 35 59 79 160 23 
PRT success rate, % N/A 35 56 42 46 
Overall PRT product inventory, % N/A 19 38 29 30 

PRT1 to PRT4 are collection configurations designed to target products that are eligible for PRT by IBS. The overall split rate is the number of products collected divided by number of collections. The products discarded/discard rate represents the products discarded due specifically to concentration failure (the TerumoBCT Platelet storage bag allows for maximum concentration of 2.1 × 109/mL). The IBS PRT success rate is the percentage of products eligible for IBS PRT treatment from the attempted single and double donations (triple collections excluded). Overall IBS PRT product inventory is the percentage of entire apheresis platelet inventory eligible for IBS PRT.

NA, not applicable.

*

Failures unknown for this time period. Split rate may be slightly lower.

Concentration failures and discards excluded from number of products collected.

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