Effect of IBS PRT settings on platelet inventory and number of theoretical PRT products
Parameter . | Time period . | |||||
---|---|---|---|---|---|---|
1 . | 2 . | 3 . | 4 . | 5 . | 6 . | |
Length, d | 21 | 12 | 14 | 20 | 40 | 30 |
Collection configuration | Original* (no PRT settings) | PRT1 | PRT2 | PRT3 | PRT4 | Normal |
Number of donations | 152 | 104 | 84 | 158 | 288 | 227 |
Number of products† | 326* | 187 | 155 | 272 | 540 | 469 |
Overall split rate | 2.14* | 1.79 | 1.85 | 1.72 | 1.88 | 2.07 |
Triple donations, % | 46 | 48 | 30 | 30 | 33 | 32 |
Double donations, % | 42 | 45 | 56 | 50 | 53 | 61 |
Single donations, % | 12 | 7 | 14 | 20 | 14 | 7 |
Products discarded | 1* | 6 | 7 | 40 | 44 | 9 |
Discard rate, % | N/A | 3 | 4 | 13 | 8 | 2 |
PRT products attempted from single and double collections | N/A | 101 | 106 | 190 | 347 | 293 |
PRT units produced | N/A | 35 | 59 | 79 | 160 | 23 |
PRT success rate, % | N/A | 35 | 56 | 42 | 46 | 8 |
Overall PRT product inventory, % | N/A | 19 | 38 | 29 | 30 | 5 |
Parameter . | Time period . | |||||
---|---|---|---|---|---|---|
1 . | 2 . | 3 . | 4 . | 5 . | 6 . | |
Length, d | 21 | 12 | 14 | 20 | 40 | 30 |
Collection configuration | Original* (no PRT settings) | PRT1 | PRT2 | PRT3 | PRT4 | Normal |
Number of donations | 152 | 104 | 84 | 158 | 288 | 227 |
Number of products† | 326* | 187 | 155 | 272 | 540 | 469 |
Overall split rate | 2.14* | 1.79 | 1.85 | 1.72 | 1.88 | 2.07 |
Triple donations, % | 46 | 48 | 30 | 30 | 33 | 32 |
Double donations, % | 42 | 45 | 56 | 50 | 53 | 61 |
Single donations, % | 12 | 7 | 14 | 20 | 14 | 7 |
Products discarded | 1* | 6 | 7 | 40 | 44 | 9 |
Discard rate, % | N/A | 3 | 4 | 13 | 8 | 2 |
PRT products attempted from single and double collections | N/A | 101 | 106 | 190 | 347 | 293 |
PRT units produced | N/A | 35 | 59 | 79 | 160 | 23 |
PRT success rate, % | N/A | 35 | 56 | 42 | 46 | 8 |
Overall PRT product inventory, % | N/A | 19 | 38 | 29 | 30 | 5 |
PRT1 to PRT4 are collection configurations designed to target products that are eligible for PRT by IBS. The overall split rate is the number of products collected divided by number of collections. The products discarded/discard rate represents the products discarded due specifically to concentration failure (the TerumoBCT Platelet storage bag allows for maximum concentration of 2.1 × 109/mL). The IBS PRT success rate is the percentage of products eligible for IBS PRT treatment from the attempted single and double donations (triple collections excluded). Overall IBS PRT product inventory is the percentage of entire apheresis platelet inventory eligible for IBS PRT.
NA, not applicable.
Failures unknown for this time period. Split rate may be slightly lower.
Concentration failures and discards excluded from number of products collected.