Table 1. MCL patient sample collection... | American Society of Hematology

Table 1.

MCL patient sample collection and its clinical parameters

MCL sample no.	Type	Status	Prior therapy	CD19⁺ cells, %	ROR1⁺ cells, %*	GeoMean ratio†
1	Classic	Relapse	Hyper-CVAD	80	80	30
2	Classic	Diagnosis		74	95	29
3	Classic	Diagnosis		86	79	14
4	Indolent	Diagnosis		95	83	18
5	Classic	Diagnosis		85	96	27
6	Classic	Relapse	Ibrutinib	78	0	1
7	Classic	Diagnosis		69	93	7
8	Indolent	Diagnosis		90	1	1
9	Blastoid	Relapse	R-CHOP	85	99	22
10	Indolent	Relapse	R-Fludarabine	95	97	51
11	Classic	Relapse	ND	95	20	31
12	Classic	Relapse	ND	71	99	32
13	Indolent	Relapse	R-CHOP	95	97	8
14	Classic	Diagnosis		80	100	45
15	Blastoid	Relapse	R-CHOP	90	20	7
16	Indolent	Relapse	R-Benda	85	99	17
17	Classic	Relapse	ND	80	97	12
18	Indolent	Diagnosis		68	95	10
19	ND	ND	ND	85	98	20
20	Classic	Diagnosis		98	83	6
21	Classic	Diagnosis		91	87	7

MCL sample no.	Type	Status	Prior therapy	CD19⁺ cells, %	ROR1⁺ cells, %*	GeoMean ratio†
1	Classic	Relapse	Hyper-CVAD	80	80	30
2	Classic	Diagnosis		74	95	29
3	Classic	Diagnosis		86	79	14
4	Indolent	Diagnosis		95	83	18
5	Classic	Diagnosis		85	96	27
6	Classic	Relapse	Ibrutinib	78	0	1
7	Classic	Diagnosis		69	93	7
8	Indolent	Diagnosis		90	1	1
9	Blastoid	Relapse	R-CHOP	85	99	22
10	Indolent	Relapse	R-Fludarabine	95	97	51
11	Classic	Relapse	ND	95	20	31
12	Classic	Relapse	ND	71	99	32
13	Indolent	Relapse	R-CHOP	95	97	8
14	Classic	Diagnosis		80	100	45
15	Blastoid	Relapse	R-CHOP	90	20	7
16	Indolent	Relapse	R-Benda	85	99	17
17	Classic	Relapse	ND	80	97	12
18	Indolent	Diagnosis		68	95	10
19	ND	ND	ND	85	98	20
20	Classic	Diagnosis		98	83	6
21	Classic	Diagnosis		91	87	7

Hyper-CVAD, hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone; ND, not determined; R-Benda, rituximab and bendamustine; R-CHOP, rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone; R-Fludarabine, rituximab and fludarabine.

From CD19⁺ cells.

†

Ratio of ROR1 GeoMean/control GeoMean.

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