Table 4.

HRs and 95% CIs for obesity and risk of progression from MGUS to MM and other LP diseases

MMMM and other LP diseases
nHR95% CInHR95% CI
Baseline BMI       
 <25.0 Ref. Ref. Ref. Ref. 
 ≥25.0 13 1.33 0.47-3.75 21 1.30 0.57-2.94 
Midlife BMI       
 <25.0 Ref. Ref. Ref. Ref. 
 ≥25.0 13 2.64 0.93-7.48 21 2.66 1.17-6.05 
Weight 18 1.10 0.84-1.44 29 1.04 0.84-1.29 
Max weight 18 1.16 0.88-1.54 29 1.15 0.93-1.43 
Percent body fat (BIA) 10 1.54 0.35-6.86 19 0.96 0.88-1.05 
Fat (BIA) 10 1.92 0.81-4.57 19 0.79 0.29-2.13 
Total body fat (CT) 17 1.00 0.98-1.02 28 1.00 0.98-1.01 
Visceral fat (CT) 17 1.00 0.96-1.05 28 0.99 0.95-1.03 
Subcutaneous fat (CT) 17 1.01 0.97-1.04 28 0.99 0.96-1.02 
Waist circumference (CT) 17 1.01 0.97-1.04 28 0.96 0.79-1.16 
Waist circumference 18 1.16 0.82-1.64 29 1.00 0.75-1.33 
MMMM and other LP diseases
nHR95% CInHR95% CI
Baseline BMI       
 <25.0 Ref. Ref. Ref. Ref. 
 ≥25.0 13 1.33 0.47-3.75 21 1.30 0.57-2.94 
Midlife BMI       
 <25.0 Ref. Ref. Ref. Ref. 
 ≥25.0 13 2.64 0.93-7.48 21 2.66 1.17-6.05 
Weight 18 1.10 0.84-1.44 29 1.04 0.84-1.29 
Max weight 18 1.16 0.88-1.54 29 1.15 0.93-1.43 
Percent body fat (BIA) 10 1.54 0.35-6.86 19 0.96 0.88-1.05 
Fat (BIA) 10 1.92 0.81-4.57 19 0.79 0.29-2.13 
Total body fat (CT) 17 1.00 0.98-1.02 28 1.00 0.98-1.01 
Visceral fat (CT) 17 1.00 0.96-1.05 28 0.99 0.95-1.03 
Subcutaneous fat (CT) 17 1.01 0.97-1.04 28 0.99 0.96-1.02 
Waist circumference (CT) 17 1.01 0.97-1.04 28 0.96 0.79-1.16 
Waist circumference 18 1.16 0.82-1.64 29 1.00 0.75-1.33 

Results were obtained with Cox proportional hazard regression. HRs for continuous variables are per SD increase.

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