HRs and 95% CIs for obesity and risk of progression from MGUS to MM and other LP diseases
. | MM . | MM and other LP diseases . | ||||
---|---|---|---|---|---|---|
n . | HR . | 95% CI . | n . | HR . | 95% CI . | |
Baseline BMI | ||||||
<25.0 | 5 | Ref. | Ref. | 8 | Ref. | Ref. |
≥25.0 | 13 | 1.33 | 0.47-3.75 | 21 | 1.30 | 0.57-2.94 |
Midlife BMI | ||||||
<25.0 | 5 | Ref. | Ref. | 8 | Ref. | Ref. |
≥25.0 | 13 | 2.64 | 0.93-7.48 | 21 | 2.66 | 1.17-6.05 |
Weight | 18 | 1.10 | 0.84-1.44 | 29 | 1.04 | 0.84-1.29 |
Max weight | 18 | 1.16 | 0.88-1.54 | 29 | 1.15 | 0.93-1.43 |
Percent body fat (BIA) | 10 | 1.54 | 0.35-6.86 | 19 | 0.96 | 0.88-1.05 |
Fat (BIA) | 10 | 1.92 | 0.81-4.57 | 19 | 0.79 | 0.29-2.13 |
Total body fat (CT) | 17 | 1.00 | 0.98-1.02 | 28 | 1.00 | 0.98-1.01 |
Visceral fat (CT) | 17 | 1.00 | 0.96-1.05 | 28 | 0.99 | 0.95-1.03 |
Subcutaneous fat (CT) | 17 | 1.01 | 0.97-1.04 | 28 | 0.99 | 0.96-1.02 |
Waist circumference (CT) | 17 | 1.01 | 0.97-1.04 | 28 | 0.96 | 0.79-1.16 |
Waist circumference | 18 | 1.16 | 0.82-1.64 | 29 | 1.00 | 0.75-1.33 |
. | MM . | MM and other LP diseases . | ||||
---|---|---|---|---|---|---|
n . | HR . | 95% CI . | n . | HR . | 95% CI . | |
Baseline BMI | ||||||
<25.0 | 5 | Ref. | Ref. | 8 | Ref. | Ref. |
≥25.0 | 13 | 1.33 | 0.47-3.75 | 21 | 1.30 | 0.57-2.94 |
Midlife BMI | ||||||
<25.0 | 5 | Ref. | Ref. | 8 | Ref. | Ref. |
≥25.0 | 13 | 2.64 | 0.93-7.48 | 21 | 2.66 | 1.17-6.05 |
Weight | 18 | 1.10 | 0.84-1.44 | 29 | 1.04 | 0.84-1.29 |
Max weight | 18 | 1.16 | 0.88-1.54 | 29 | 1.15 | 0.93-1.43 |
Percent body fat (BIA) | 10 | 1.54 | 0.35-6.86 | 19 | 0.96 | 0.88-1.05 |
Fat (BIA) | 10 | 1.92 | 0.81-4.57 | 19 | 0.79 | 0.29-2.13 |
Total body fat (CT) | 17 | 1.00 | 0.98-1.02 | 28 | 1.00 | 0.98-1.01 |
Visceral fat (CT) | 17 | 1.00 | 0.96-1.05 | 28 | 0.99 | 0.95-1.03 |
Subcutaneous fat (CT) | 17 | 1.01 | 0.97-1.04 | 28 | 0.99 | 0.96-1.02 |
Waist circumference (CT) | 17 | 1.01 | 0.97-1.04 | 28 | 0.96 | 0.79-1.16 |
Waist circumference | 18 | 1.16 | 0.82-1.64 | 29 | 1.00 | 0.75-1.33 |
Results were obtained with Cox proportional hazard regression. HRs for continuous variables are per SD increase.