Prevalence of AL amyloidosis in years 2007 to 2011
| . | . | No. of cases per million (numerator/denominator*) . | ||||
|---|---|---|---|---|---|---|
| Sex . | Age, y . | 2007 . | 2008 . | 2009 . | 2010 . | 2011 . |
| Female | 18-34 | 1.5 (5/3 414 356) | 0.6 (3/4 924 396) | 0.6 (3/5 358 001) | 2.3 (12/5 139 252) | 2.3 (13/5 768 546) |
| 35-54 | 6.6 (37/5 617 369) | 8.3 (65/7 859 203) | 11.3 (97/8 565 752) | 13.2 (108/8 210 092) | 11.6 (100/8 586 461) | |
| 55-64 | 26.5 (61/2 299 588) | 35.1 (114/3 244 578) | 35.0 (128/3 658 984) | 38.6 (140/3 627 100) | 44.5 (177/3 981 344) | |
| 65+ | 54.4 (65/1 195 298) | 47.9 (94/1 963 731) | 57.5 (118/2 052 079) | 55.5 (120/2 162 661) | 69.3 (177/2 555 455) | |
| All female | 13.4 (168/12 526 611) | 15.3 (276/17 991 908) | 17.6 (346/19 634 816) | 19.9 (380/19 139 105) | 22.4 (467/20 891 806) | |
| Male | 18-34 | 0.0 (0/3 152 398) | 0.4 (2/4 508 032) | 0.6 (3/4 876 950) | 1.3 (6/4 668 942) | 0.7 (4/5 442 930) |
| 35-54 | 7.2 (36/5 029 837) | 9.5 (67/7 060 318) | 10.3 (79/7 690 284) | 12.2 (90/7 360 450) | 12.2 (95/7 782 789) | |
| 55-64 | 31.9 (67/2 099 846) | 39.2 (116/2 957 222) | 46.6 (154/3 308 173) | 49.3 (160/3 244 501) | 53.1 (189/3 556 632) | |
| 65+ | 100.4 (97/965 927) | 85.4 (134/1 569 003) | 95.3 (159/1 667 958) | 116.3 (201/1 728 898) | 130.7 (266/2 035 214) | |
| All male | 17.8 (200/11 248 008) | 19.8 (319/16 094 575) | 22.5 (395/17 543 365) | 26.9 (457/17 002 791) | 29.4 (554/18 817 565) | |
| All sex | 18-34 | 0.8 (5/6 566 754) | 0.5 (5/9 432 428) | 0.6 (6/10 234 951) | 1.8 (18/9 808 194) | 1.5 (17/11 211 476) |
| 35-54 | 6.9 (73/10 647 206) | 8.8 (132/14 919 521) | 10.8 (176/16 256 036) | 12.7 (198/15 570 542) | 11.9 (195/16 369 250) | |
| 55-64 | 29.1 (128/4 399 434) | 37.1 (230/6 201 800) | 40.5 (282/6 967 157) | 43.7 (300/6 871 601) | 48.6 (366/7 537 976) | |
| 65+ | 75.0 (162/2 161 225) | 64.5 (228/3 532 734) | 74.5 (277/3 720 037) | 82.5 (321/3 891 559) | 96.5 (443/4 590 669) | |
| All patients | 15.5 (368/23 774 619) | 17.5 (595/34 086 483) | 9.9 (741/37 178 181) | 23.2 (837/36 141 896) | 25.7 (1021/39 709 371) | |
| US adult population | Age-sex adjusted†rate, no. of cases per million | |||||
| Female | 17.3 | 17.8 | 29.7 | 22.0 | 25.0 | |
| Male | 23.0 | 22.9 | 25.9 | 30.4 | 33.1 | |
| All | 20.1 | 20.2 | 23.2 | 26.1 | 28.9 | |
| . | . | No. of cases per million (numerator/denominator*) . | ||||
|---|---|---|---|---|---|---|
| Sex . | Age, y . | 2007 . | 2008 . | 2009 . | 2010 . | 2011 . |
| Female | 18-34 | 1.5 (5/3 414 356) | 0.6 (3/4 924 396) | 0.6 (3/5 358 001) | 2.3 (12/5 139 252) | 2.3 (13/5 768 546) |
| 35-54 | 6.6 (37/5 617 369) | 8.3 (65/7 859 203) | 11.3 (97/8 565 752) | 13.2 (108/8 210 092) | 11.6 (100/8 586 461) | |
| 55-64 | 26.5 (61/2 299 588) | 35.1 (114/3 244 578) | 35.0 (128/3 658 984) | 38.6 (140/3 627 100) | 44.5 (177/3 981 344) | |
| 65+ | 54.4 (65/1 195 298) | 47.9 (94/1 963 731) | 57.5 (118/2 052 079) | 55.5 (120/2 162 661) | 69.3 (177/2 555 455) | |
| All female | 13.4 (168/12 526 611) | 15.3 (276/17 991 908) | 17.6 (346/19 634 816) | 19.9 (380/19 139 105) | 22.4 (467/20 891 806) | |
| Male | 18-34 | 0.0 (0/3 152 398) | 0.4 (2/4 508 032) | 0.6 (3/4 876 950) | 1.3 (6/4 668 942) | 0.7 (4/5 442 930) |
| 35-54 | 7.2 (36/5 029 837) | 9.5 (67/7 060 318) | 10.3 (79/7 690 284) | 12.2 (90/7 360 450) | 12.2 (95/7 782 789) | |
| 55-64 | 31.9 (67/2 099 846) | 39.2 (116/2 957 222) | 46.6 (154/3 308 173) | 49.3 (160/3 244 501) | 53.1 (189/3 556 632) | |
| 65+ | 100.4 (97/965 927) | 85.4 (134/1 569 003) | 95.3 (159/1 667 958) | 116.3 (201/1 728 898) | 130.7 (266/2 035 214) | |
| All male | 17.8 (200/11 248 008) | 19.8 (319/16 094 575) | 22.5 (395/17 543 365) | 26.9 (457/17 002 791) | 29.4 (554/18 817 565) | |
| All sex | 18-34 | 0.8 (5/6 566 754) | 0.5 (5/9 432 428) | 0.6 (6/10 234 951) | 1.8 (18/9 808 194) | 1.5 (17/11 211 476) |
| 35-54 | 6.9 (73/10 647 206) | 8.8 (132/14 919 521) | 10.8 (176/16 256 036) | 12.7 (198/15 570 542) | 11.9 (195/16 369 250) | |
| 55-64 | 29.1 (128/4 399 434) | 37.1 (230/6 201 800) | 40.5 (282/6 967 157) | 43.7 (300/6 871 601) | 48.6 (366/7 537 976) | |
| 65+ | 75.0 (162/2 161 225) | 64.5 (228/3 532 734) | 74.5 (277/3 720 037) | 82.5 (321/3 891 559) | 96.5 (443/4 590 669) | |
| All patients | 15.5 (368/23 774 619) | 17.5 (595/34 086 483) | 9.9 (741/37 178 181) | 23.2 (837/36 141 896) | 25.7 (1021/39 709 371) | |
| US adult population | Age-sex adjusted†rate, no. of cases per million | |||||
| Female | 17.3 | 17.8 | 29.7 | 22.0 | 25.0 | |
| Male | 23.0 | 22.9 | 25.9 | 30.4 | 33.1 | |
| All | 20.1 | 20.2 | 23.2 | 26.1 | 28.9 | |