Table 3.

Multivariate model

Multivariate model AMultivariate model B
ParameterRisk ratio (95% CI)PParameterRisk ratio (95% CI)P
λ Light chain 2.3 (1.5-3.7) .0001 λ Light chain 2.1 (1.4-3.4) .0004 
Mayo stage 2012 III/IV vs I/II 2.5 (1.7-3.8) <.0001 Mayo stage 2004 II/III vs I 2.1 (1.4-3.0) <.0001 
Conditioning dose 200 vs <200 mg/m2 0.4 (0.3-0.5) <.0001 Conditioning dose 200 vs <200 mg/m2 0.4 (0.3-0.6) <.0001 
BMPCs ≥10% 1.5 (1.1-2.1) .015 BMPCs ≥10% 1.6 (1.2-2.2) .005 
ASCT date <2010 vs ≥2010 1.5 (0.99-2.3) .06 ASCT date <2010 vs ≥2010 1.6 (1.0-2.4) .03 
>2 organs involved 0.8 (0.5-1.3) .37 >2 organs involved 0.8 (0.5-1.3) .44 
Male sex 1.4 (0.99-2.0) .06 Male sex 1.4 (1.0-2.0) .048 
Age ≥65 y 1.1 (0.7-1.5) .72 Age ≥65 y 1.1 (0.7-1.6) .66 
Multivariate model AMultivariate model B
ParameterRisk ratio (95% CI)PParameterRisk ratio (95% CI)P
λ Light chain 2.3 (1.5-3.7) .0001 λ Light chain 2.1 (1.4-3.4) .0004 
Mayo stage 2012 III/IV vs I/II 2.5 (1.7-3.8) <.0001 Mayo stage 2004 II/III vs I 2.1 (1.4-3.0) <.0001 
Conditioning dose 200 vs <200 mg/m2 0.4 (0.3-0.5) <.0001 Conditioning dose 200 vs <200 mg/m2 0.4 (0.3-0.6) <.0001 
BMPCs ≥10% 1.5 (1.1-2.1) .015 BMPCs ≥10% 1.6 (1.2-2.2) .005 
ASCT date <2010 vs ≥2010 1.5 (0.99-2.3) .06 ASCT date <2010 vs ≥2010 1.6 (1.0-2.4) .03 
>2 organs involved 0.8 (0.5-1.3) .37 >2 organs involved 0.8 (0.5-1.3) .44 
Male sex 1.4 (0.99-2.0) .06 Male sex 1.4 (1.0-2.0) .048 
Age ≥65 y 1.1 (0.7-1.5) .72 Age ≥65 y 1.1 (0.7-1.6) .66 

CI, confidence interval.

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