Baseline characteristics of patients with del(11q) disease
| Variable . | FCR, N = 27 . | FCR+L, N = 31 . | P* . |
|---|---|---|---|
| Median age (range), y | 60 (41-78) | 59 (30-75) | .50 |
| Sex, no. (%) | .27 | ||
| Male | 16 (59) | 23 (74) | |
| Female | 11 (41) | 8 (26) | |
| Rai stage, no. (%) | .25 | ||
| I | 4 (15) | 8 (26) | |
| II | 8 (30) | 14 (45) | |
| III | 6 (22) | 4 (13) | |
| IV | 9 (33) | 5 (16) | |
| ECOG PS, no. (%) | .89 | ||
| 0 | 16 (59) | 17 (55) | |
| 1 | 10 (37) | 13 (42) | |
| 2 | 1 (4) | 1 (3) | |
| Median hemoglobin (range), g/L | 121 (70-154) | 120 (35-151) | .83 |
| Median platelets (range), ×109/L | 125 (37-275) | 159 (44-375) | .34 |
| Median WBC (range), ×109/L | 69.1 (10.6-289.0) | 77.1 (6.3-244.9) | .86 |
| B2M above normal, no. (%) | .51 | ||
| No | 7 (29) | 5 (18) | |
| Yes | 17 (71) | 23 (82) | |
| LDH above normal, no. (%) | .59 | ||
| No | 15 (58) | 14 (48) | |
| Yes | 11 (42) | 15 (52) | |
| Serum creatinine above normal, no. (%) | 1.00 | ||
| No | 25 (96) | 28 (93) | |
| Yes | 1 (4) | 2 (7) | |
| Palpable splenomegaly, no. (%) | .79 | ||
| No | 14 (52) | 18 (58) | |
| Yes | 13 (48) | 13 (42) | |
| Palpable hepatomegaly, no. (%) | .36 | ||
| No | 26 (96) | 26 (87) | |
| Yes | 1 (4) | 4 (13) | |
| Adenopathy, no. (%) | 1.00 | ||
| No adenopathy | 0 (0) | 0 (0) | |
| Yes, lymph node <5 cm | 12 (50) | 15 (52) | |
| Yes, lymph node 5-10 cm | 10 (42) | 12 (41) | |
| Yes, lymph node >10 cm | 2 (8) | 2 (7) | |
| del(17p), no. (%) | 1.00 | ||
| Absent | 26 (96) | 29 (94) | |
| Present | 1 (4) | 2 (6) | |
| Trisomy 12, no. (%) | .74 | ||
| Absent | 23 (85) | 25 (81) | |
| Present | 4 (15) | 6 (19) | |
| del(13q), no. (%) | .18 | ||
| Absent | 13 (48) | 9 (29) | |
| Present | 14 (52) | 22 (71) |
| Variable . | FCR, N = 27 . | FCR+L, N = 31 . | P* . |
|---|---|---|---|
| Median age (range), y | 60 (41-78) | 59 (30-75) | .50 |
| Sex, no. (%) | .27 | ||
| Male | 16 (59) | 23 (74) | |
| Female | 11 (41) | 8 (26) | |
| Rai stage, no. (%) | .25 | ||
| I | 4 (15) | 8 (26) | |
| II | 8 (30) | 14 (45) | |
| III | 6 (22) | 4 (13) | |
| IV | 9 (33) | 5 (16) | |
| ECOG PS, no. (%) | .89 | ||
| 0 | 16 (59) | 17 (55) | |
| 1 | 10 (37) | 13 (42) | |
| 2 | 1 (4) | 1 (3) | |
| Median hemoglobin (range), g/L | 121 (70-154) | 120 (35-151) | .83 |
| Median platelets (range), ×109/L | 125 (37-275) | 159 (44-375) | .34 |
| Median WBC (range), ×109/L | 69.1 (10.6-289.0) | 77.1 (6.3-244.9) | .86 |
| B2M above normal, no. (%) | .51 | ||
| No | 7 (29) | 5 (18) | |
| Yes | 17 (71) | 23 (82) | |
| LDH above normal, no. (%) | .59 | ||
| No | 15 (58) | 14 (48) | |
| Yes | 11 (42) | 15 (52) | |
| Serum creatinine above normal, no. (%) | 1.00 | ||
| No | 25 (96) | 28 (93) | |
| Yes | 1 (4) | 2 (7) | |
| Palpable splenomegaly, no. (%) | .79 | ||
| No | 14 (52) | 18 (58) | |
| Yes | 13 (48) | 13 (42) | |
| Palpable hepatomegaly, no. (%) | .36 | ||
| No | 26 (96) | 26 (87) | |
| Yes | 1 (4) | 4 (13) | |
| Adenopathy, no. (%) | 1.00 | ||
| No adenopathy | 0 (0) | 0 (0) | |
| Yes, lymph node <5 cm | 12 (50) | 15 (52) | |
| Yes, lymph node 5-10 cm | 10 (42) | 12 (41) | |
| Yes, lymph node >10 cm | 2 (8) | 2 (7) | |
| del(17p), no. (%) | 1.00 | ||
| Absent | 26 (96) | 29 (94) | |
| Present | 1 (4) | 2 (6) | |
| Trisomy 12, no. (%) | .74 | ||
| Absent | 23 (85) | 25 (81) | |
| Present | 4 (15) | 6 (19) | |
| del(13q), no. (%) | .18 | ||
| Absent | 13 (48) | 9 (29) | |
| Present | 14 (52) | 22 (71) |
Percent values are calculated out of the number of patients with nonmissing data in each category.
Abbreviations are explained in Table 2.
Fisher’s exact and Kruskal-Wallis P values are presented for categoric and continuous variables, respectively.