Hazard ratios for death in a multivariable model
| Covariate . | P . | HR . | 95% CI of HR . |
|---|---|---|---|
| TED (quantifiable vs NoTED) | .0001 | 4.9 | 2.1-11.0 |
| IPSS-R (high vs low) | .0035 | 3.7 | 1.5-9.0 |
| IPSS-R (very high vs low) | .031 | 2.7 | 1.0-6.8 |
| CUX1 (absent vs present) | .0157 | 3.5 | 1.2-9.6 |
| STAG2 (absent vs present) | .045 | 3.0 | 1.0-9.1 |
| Covariate . | P . | HR . | 95% CI of HR . |
|---|---|---|---|
| TED (quantifiable vs NoTED) | .0001 | 4.9 | 2.1-11.0 |
| IPSS-R (high vs low) | .0035 | 3.7 | 1.5-9.0 |
| IPSS-R (very high vs low) | .031 | 2.7 | 1.0-6.8 |
| CUX1 (absent vs present) | .0157 | 3.5 | 1.2-9.6 |
| STAG2 (absent vs present) | .045 | 3.0 | 1.0-9.1 |
The model includes TED (quantifiable or not), IPSS-R (very low, low, intermediate, high, and very high), M:E ratio (<5 and ≥5), and presence or absence of mutation in CUX1, RUNX1, SRSF2, and STAG2.
CI, confidence interval; HR, hazard ratio.