Nonlimiting toxicity grade 3-4
| Valproate dose, mg/kg per day . | N . | Anemia . | Neutropenia . | Thrombocytopenia . | Infection . | Neuropathy . |
|---|---|---|---|---|---|---|
| 30 | 3 | 1 | 2 | 1 | 1 | 0 |
| 60 | 20 | 2 | 15 | 5 | 4 | 1 |
| 80 | 3 | 0 | 5 | 2 | 3 | 1 |
| 100 | 6 | 0 | 4 | 2 | 0 | 1 |
| 120 | 1 | 0 | 1 | 1 | 1 | 0 |
| Valproate dose, mg/kg per day . | N . | Anemia . | Neutropenia . | Thrombocytopenia . | Infection . | Neuropathy . |
|---|---|---|---|---|---|---|
| 30 | 3 | 1 | 2 | 1 | 1 | 0 |
| 60 | 20 | 2 | 15 | 5 | 4 | 1 |
| 80 | 3 | 0 | 5 | 2 | 3 | 1 |
| 100 | 6 | 0 | 4 | 2 | 0 | 1 |
| 120 | 1 | 0 | 1 | 1 | 1 | 0 |
Number of events in all cycles is shown.