Table 1. CBC parameters for the murine... | American Society of Hematology

Table 1.

CBC parameters for the murine models used in this study

	WBC, × 10⁹/L	Lymphocytes, × 10⁹/L	Monocytes, × 10⁹/L	RBCs, × 10¹²/L	Platelets, × 10⁹/L
WT	8.24 ± 1.83	7.7 ± 1.71	0.10 ± 0.00	9.75 ± 0.29	800.0 ± 110.9
KI/WT	10.56 ± 5.14	8.97 ± 4.03	0.33 ± 0.36	9.22 ± 0.51	897.9 ± 184.0
KI/KI	20.24 ± 5.65*	17.27 ± 4.45†	0.60 ± 0.26†	9.39 ± 0.95	752.3 ± 57.9
Ts1Rhr	10.53 ± 1.42	9.32 ± 1.04	0.15 ± 0.07	8.46 ± 0.54*	1222.5 ± 81.5*
Ts1Rhr-KI/WT	11.57 ± 3.63	10.3 ± 3.31	0.33 ± 0.24	7.93 ± 0.58‡	1189.6 ± 493.9
Ts1Rhr-KI/KI	35.97 ± 9.29*§	27.62 ± 5.11*	1.80 ± 0.77†§	7.24 ± 0.82†§	779.2 ± 222.4*

	WBC, × 10⁹/L	Lymphocytes, × 10⁹/L	Monocytes, × 10⁹/L	RBCs, × 10¹²/L	Platelets, × 10⁹/L
WT	8.24 ± 1.83	7.7 ± 1.71	0.10 ± 0.00	9.75 ± 0.29	800.0 ± 110.9
KI/WT	10.56 ± 5.14	8.97 ± 4.03	0.33 ± 0.36	9.22 ± 0.51	897.9 ± 184.0
KI/KI	20.24 ± 5.65*	17.27 ± 4.45†	0.60 ± 0.26†	9.39 ± 0.95	752.3 ± 57.9
Ts1Rhr	10.53 ± 1.42	9.32 ± 1.04	0.15 ± 0.07	8.46 ± 0.54*	1222.5 ± 81.5*
Ts1Rhr-KI/WT	11.57 ± 3.63	10.3 ± 3.31	0.33 ± 0.24	7.93 ± 0.58‡	1189.6 ± 493.9
Ts1Rhr-KI/KI	35.97 ± 9.29*§	27.62 ± 5.11*	1.80 ± 0.77†§	7.24 ± 0.82†§	779.2 ± 222.4*

Data are mean ± standard deviation; P values were calculated by using an unpaired Student t test (3 to 11 mice per group). All animals were 6 to 8 months old.

CBC, complete blood count; WBC, white blood cell count.

P < .01 compared to WT or Ts1Rhr.

†

P < .05 compared to WT or Ts1Rhr.

‡

P < .01 compared to euploid Jak3^KI/WT or Jak3^KI/KI.

P < .05 compared to euploid Jak3^KI/WT or Jak3^KI/KI.

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