Transplant outcomes
| Outcome . | Entire cohort . | MAC . | RIC . | P . |
|---|---|---|---|---|
| Incidence of aGVHD, n (%) | ||||
| Grade I | 140 (18) | 67 (21.8) | 73 (15.6) | .0129 |
| Grade II | 110 (14.2) | 52 (16.9) | 58 (12.4) | |
| Grade III | 54 (7) | 26 (8.5) | 28 (6) | |
| Grade IV | 30 (3.9) | 9 (2.9) | 21 (4.5) | |
| None | 433 (55.8) | 149 (48.5) | 284 (60.6) | |
| Present grade unknown | 9 (1.2) | 4 (1.3) | 5 (1.1) | |
| Chronic GVHD, n (%) | ||||
| No | 467 (63.9) | 187 (64.9) | 280 (63.2) | |
| Yes | 264 (36.1) | 101 (35.1) | 163 (36.8) | .6923 |
| 2-y OS (95% CI), % | 46 (43-50) | 50 (45-56) | 44 (39-49) | .039 |
| 2-y LFS (95% CI), % | 40 (37-44) | 45 (39-51) | 37 (33-42) | .029 |
| 2-y cumulative incidence of relapse (95% CI), % | 37 (33-40) | 32 (27-38) | 40 (36-45) | .0341 |
| 2-y cumulative incidence of NRM (95% CI), % | 23 (20-26) | 23 (19-28) | 23 (19-27) | .8561 |
| aGVHD at 100 d (95% CI), % | 11 (9-13) | 12 (8-15) | 10 (8-13) | .6443 |
| 2-y cumulative incidence of cGVHD (95% CI), % | 39 (35-42) | 36 (31-42) | 40 (35-45) | .3906 |
| 2-y cumulative incidence of extensive cGVHD (95% CI), % | 17 (15-20) | 17 (13-22) | 17 (14-21) | .8851 |
| Outcome . | Entire cohort . | MAC . | RIC . | P . |
|---|---|---|---|---|
| Incidence of aGVHD, n (%) | ||||
| Grade I | 140 (18) | 67 (21.8) | 73 (15.6) | .0129 |
| Grade II | 110 (14.2) | 52 (16.9) | 58 (12.4) | |
| Grade III | 54 (7) | 26 (8.5) | 28 (6) | |
| Grade IV | 30 (3.9) | 9 (2.9) | 21 (4.5) | |
| None | 433 (55.8) | 149 (48.5) | 284 (60.6) | |
| Present grade unknown | 9 (1.2) | 4 (1.3) | 5 (1.1) | |
| Chronic GVHD, n (%) | ||||
| No | 467 (63.9) | 187 (64.9) | 280 (63.2) | |
| Yes | 264 (36.1) | 101 (35.1) | 163 (36.8) | .6923 |
| 2-y OS (95% CI), % | 46 (43-50) | 50 (45-56) | 44 (39-49) | .039 |
| 2-y LFS (95% CI), % | 40 (37-44) | 45 (39-51) | 37 (33-42) | .029 |
| 2-y cumulative incidence of relapse (95% CI), % | 37 (33-40) | 32 (27-38) | 40 (36-45) | .0341 |
| 2-y cumulative incidence of NRM (95% CI), % | 23 (20-26) | 23 (19-28) | 23 (19-27) | .8561 |
| aGVHD at 100 d (95% CI), % | 11 (9-13) | 12 (8-15) | 10 (8-13) | .6443 |
| 2-y cumulative incidence of cGVHD (95% CI), % | 39 (35-42) | 36 (31-42) | 40 (35-45) | .3906 |
| 2-y cumulative incidence of extensive cGVHD (95% CI), % | 17 (15-20) | 17 (13-22) | 17 (14-21) | .8851 |