Table 3. Autologous versus allogeneic... | American Society of Hematology

Table 3.

Autologous versus allogeneic stem cell transplantation (SCT) for lymphoid diseases.

		Allogeneic SCT
Disease	Autologous SCT	Nonmyeloablative	High-dose Chemotherapy
Abbreviations: DLCL, diffuse large-cell leukemia; FL, follicular lymphoma; MCL, mantle cell lymphoma; CLL, chronic lymphocytic leukemia
DLCL	Treatment of choice for first chemosensitive relapse	Advanced relapse After failure of auto SCT	Refractory disease in young patients
FL	First chemosensitive relapse	Advanced relapse After failure of auto SCT	Refractory disease in young patients
MCL	First remission	Relapsed chemosensitive disease	Refractory disease in young patients
CLL	No defined role	In first remission if no complete response to conventional chemotherapy or poor prognostic features (del 17p, ZAP-70, unmutated heavy chain genes) Relapsed disease Richter’s	Refractory disease in young patients

		Allogeneic SCT
Disease	Autologous SCT	Nonmyeloablative	High-dose Chemotherapy
Abbreviations: DLCL, diffuse large-cell leukemia; FL, follicular lymphoma; MCL, mantle cell lymphoma; CLL, chronic lymphocytic leukemia
DLCL	Treatment of choice for first chemosensitive relapse	Advanced relapse After failure of auto SCT	Refractory disease in young patients
FL	First chemosensitive relapse	Advanced relapse After failure of auto SCT	Refractory disease in young patients
MCL	First remission	Relapsed chemosensitive disease	Refractory disease in young patients
CLL	No defined role	In first remission if no complete response to conventional chemotherapy or poor prognostic features (del 17p, ZAP-70, unmutated heavy chain genes) Relapsed disease Richter’s	Refractory disease in young patients