Table 1. Favorable and adverse effects... | American Society of Hematology

Table 1.

Favorable and adverse effects of chronic transfusion in children with sickle cell anemia with elevated velocities as determined by transcranial Doppler untrasonography (TCD).¹⁰ ^–¹²

Favorable Effects	Adverse Effects
Decreased strokes Decreased silent infarcts Decreased pain events Decreased acute chest syndrome Improved growth Decreased hemolysis	Increased ferritin Increased alloimmunization ? Increased exposure to pathogens

Favorable Effects	Adverse Effects
Decreased strokes Decreased silent infarcts Decreased pain events Decreased acute chest syndrome Improved growth Decreased hemolysis	Increased ferritin Increased alloimmunization ? Increased exposure to pathogens

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