TNMB (tumor, node, metastasis, blood) classification for patients with mycosis fungoides and Sézary syndrome.
T (skin) |
T1 limited patch/plaque (<10% of BSA) |
T2 generalized patch/plaque (>10% of BSA) |
T3 tumors |
T4 generalized erythroderma |
N (nodes) |
N0 no clinically abnormal peripheral lymph nodes |
N1 clinically abnormal peripheral lymph nodes |
NP0 biopsy performed, not CTCL |
NP1 biopsy performed, CTCL |
LN0 uninvolved |
LN1 reactive lymph node |
LN2 dermatopathic node, small clusters of convoluted cells (< 6 cells per cluster) |
LN3* dermatopathic node, large clusters of convoluted cells (> 6 cells per cluster) |
LN4* lymph node effacement |
M (viscera) |
M0 no visceral metastasis |
M1 visceral metastasis |
B (blood) |
B0 atypical circulating cells not present (<5%) |
B1 atypical circulating cells present (>5%) |
T (skin) |
T1 limited patch/plaque (<10% of BSA) |
T2 generalized patch/plaque (>10% of BSA) |
T3 tumors |
T4 generalized erythroderma |
N (nodes) |
N0 no clinically abnormal peripheral lymph nodes |
N1 clinically abnormal peripheral lymph nodes |
NP0 biopsy performed, not CTCL |
NP1 biopsy performed, CTCL |
LN0 uninvolved |
LN1 reactive lymph node |
LN2 dermatopathic node, small clusters of convoluted cells (< 6 cells per cluster) |
LN3* dermatopathic node, large clusters of convoluted cells (> 6 cells per cluster) |
LN4* lymph node effacement |
M (viscera) |
M0 no visceral metastasis |
M1 visceral metastasis |
B (blood) |
B0 atypical circulating cells not present (<5%) |
B1 atypical circulating cells present (>5%) |