Laboratory and clinical features of 27 patients with T-LGLL
| Patient no. . | Sex/Age (y) . | WBC (×109/L) . | ANC (×109/L) . | Hb (g/dL) . | Ly (×109/L) . | LGL (% Ly) . | TCR gene analysis . | Relevant Vβ expression . | Clinical course . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | M/48 | 5.9 | 1.1 | 11.3 | 4.8 | 70 | C | 5.1 | Indolent |
| 2 | M/72 | 6.1 | 1.0 | 10.1 | 4.5 | 47 | C | 17 | Indolent |
| 3 | M/58 | 9.3 | 2.2 | 11.5 | 6.5 | 40 | C | 3 | Indolent |
| 4 | F/62 | 9.8 | 2.3 | 12.3 | 6.9 | 61 | C | NF | Indolent |
| 5 | M/65 | 7.8 | 1.5 | 11.2 | 5.7 | 59 | C | NF | Indolent |
| 6 | F/53 | 8.5 | 2.1 | 11.5 | 5.3 | 40 | C | 3 | Indolent |
| 7 | F/58 | 7.4 | 1.8 | 10.9 | 5.1 | 67 | C | NF | Indolent |
| 8 | M/74 | 9.5 | 2.7 | 11.6 | 6.2 | 60 | C | NF | Indolent |
| 9 | M/63 | 9.1 | 1.2 | 10.5 | 7.1 | 75 | C | 13.1 | Indolent |
| 10 | F/53 | 6.7 | 1.1 | 11.2 | 4.7 | 60 | C | 17 | Indolent |
| 11 | F/45 | 8.8 | 1.9 | 11.6 | 6.5 | 55 | C | 4 | Indolent |
| 12 | M/53 | 12.9 | 2.2 | 11.7 | 8.9 | 90 | C | NF | Indolent |
| 13 | F/78 | 10.3 | 1.8 | 10.9 | 7.8 | 65 | C | NF | Indolent |
| 14 | F/50 | 9.6 | 2.1 | 11.7 | 6.9 | 71 | C | 17 | Indolent |
| 15 | F/75 | 9.7 | 1.7 | 12.3 | 7.5 | 79 | C | NF | Indolent |
| 16 | M/65 | 9.8 | 1.5 | 11.6 | 7.5 | 60 | C | NF | Indolent |
| 17 | F/69 | 8.4 | 1.0 | 11.9 | 6.8 | 77 | C | NF | Indolent |
| 18 | F/58 | 7.6 | 1.1 | 11.2 | 5.7 | 51 | C | 14 and 8 | Indolent |
| 19 | M/59 | 8.1 | 2.5 | 12.5 | 5.2 | 57 | C | 20 | Indolent |
| 20 | M/66 | 9.6 | 1.3 | 12.3 | 7.4 | 86 | C | 1 | Indolent |
| 21 | M/66 | 9.3 | 1.9 | 10.6 | 6.5 | 52 | C | NF | Indolent |
| 22 | F/57 | 7.5 | 1.8 | 11.1 | 5.1 | 45 | C | NF | Indolent |
| 23 | F/76 | 9.7 | 0.7 | 11.4 | 8.3 | 80 | C | NF | Indolent |
| 24 | M/54 | 8.6 | 1.1 | 12.5 | 7.1 | 80 | C | NF | Indolent |
| 25 | F/70 | 8.4 | 1.5 | 11.3 | 6.1 | 60 | C | NF | Indolent |
| 26 | M/79 | 9.1 | 1.4 | 12.1 | 7.0 | 74 | C | 17 | Indolent |
| 27 | F/62 | 10.2 | 1.0 | 11.7 | 8.8 | 89 | C | 5.3 | Indolent |
| Patient no. . | Sex/Age (y) . | WBC (×109/L) . | ANC (×109/L) . | Hb (g/dL) . | Ly (×109/L) . | LGL (% Ly) . | TCR gene analysis . | Relevant Vβ expression . | Clinical course . |
|---|---|---|---|---|---|---|---|---|---|
| 1 | M/48 | 5.9 | 1.1 | 11.3 | 4.8 | 70 | C | 5.1 | Indolent |
| 2 | M/72 | 6.1 | 1.0 | 10.1 | 4.5 | 47 | C | 17 | Indolent |
| 3 | M/58 | 9.3 | 2.2 | 11.5 | 6.5 | 40 | C | 3 | Indolent |
| 4 | F/62 | 9.8 | 2.3 | 12.3 | 6.9 | 61 | C | NF | Indolent |
| 5 | M/65 | 7.8 | 1.5 | 11.2 | 5.7 | 59 | C | NF | Indolent |
| 6 | F/53 | 8.5 | 2.1 | 11.5 | 5.3 | 40 | C | 3 | Indolent |
| 7 | F/58 | 7.4 | 1.8 | 10.9 | 5.1 | 67 | C | NF | Indolent |
| 8 | M/74 | 9.5 | 2.7 | 11.6 | 6.2 | 60 | C | NF | Indolent |
| 9 | M/63 | 9.1 | 1.2 | 10.5 | 7.1 | 75 | C | 13.1 | Indolent |
| 10 | F/53 | 6.7 | 1.1 | 11.2 | 4.7 | 60 | C | 17 | Indolent |
| 11 | F/45 | 8.8 | 1.9 | 11.6 | 6.5 | 55 | C | 4 | Indolent |
| 12 | M/53 | 12.9 | 2.2 | 11.7 | 8.9 | 90 | C | NF | Indolent |
| 13 | F/78 | 10.3 | 1.8 | 10.9 | 7.8 | 65 | C | NF | Indolent |
| 14 | F/50 | 9.6 | 2.1 | 11.7 | 6.9 | 71 | C | 17 | Indolent |
| 15 | F/75 | 9.7 | 1.7 | 12.3 | 7.5 | 79 | C | NF | Indolent |
| 16 | M/65 | 9.8 | 1.5 | 11.6 | 7.5 | 60 | C | NF | Indolent |
| 17 | F/69 | 8.4 | 1.0 | 11.9 | 6.8 | 77 | C | NF | Indolent |
| 18 | F/58 | 7.6 | 1.1 | 11.2 | 5.7 | 51 | C | 14 and 8 | Indolent |
| 19 | M/59 | 8.1 | 2.5 | 12.5 | 5.2 | 57 | C | 20 | Indolent |
| 20 | M/66 | 9.6 | 1.3 | 12.3 | 7.4 | 86 | C | 1 | Indolent |
| 21 | M/66 | 9.3 | 1.9 | 10.6 | 6.5 | 52 | C | NF | Indolent |
| 22 | F/57 | 7.5 | 1.8 | 11.1 | 5.1 | 45 | C | NF | Indolent |
| 23 | F/76 | 9.7 | 0.7 | 11.4 | 8.3 | 80 | C | NF | Indolent |
| 24 | M/54 | 8.6 | 1.1 | 12.5 | 7.1 | 80 | C | NF | Indolent |
| 25 | F/70 | 8.4 | 1.5 | 11.3 | 6.1 | 60 | C | NF | Indolent |
| 26 | M/79 | 9.1 | 1.4 | 12.1 | 7.0 | 74 | C | 17 | Indolent |
| 27 | F/62 | 10.2 | 1.0 | 11.7 | 8.8 | 89 | C | 5.3 | Indolent |
ANC, absolute neutrophil count; C, clonal rearrangement of TCR genes; F, female; Hb, hemoglobin; LGL, large granular lymphocyte; Ly, lymphocytes; M, male; NF, not found; TCR, T-cell receptor; WBC, white blood cell.