Table 1 Univariate and multivariable... | American Society of Hematology

Table 1

Univariate and multivariable models for posttransplant outcome

Cytogenetic risk5	No. of patients†	Relapse			Overall mortality			Nonrelapse mortality			Treatment failure*
Cytogenetic risk5	No. of patients†	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Univariate model
Good	270	1			1			1			1
Intermediate	108	0.98	0.62-1.57	.94	1.11	0.82-1.50	.50	1.21	0.83-1.76	.33	1.11	0.83-1.49	.49
Poor	73	1.54	0.98-2.43	.06	0.98	0.68-1.41	.92	0.75	0.45-1.26	.28	1.09	0.78-1.53	.62
Very poor	82	5.07	3.40-7.56	<.0001	3.35	2.51-4.46	<.0001	2.95	1.97-4.41	<.0001	3.83	2.89-5.08	<.0001
Multivariable model adjusting for blast count, hemoglobin, platelet count, neutrophil count, and LDH
Good	270	1			1			1			1
Intermediate	108	0.94	0.58-1.51	.80	1.02	0.75-1.39	.89	1.08	0.74-1.59	.68	1.03	0.77-1.39	.83
Poor	73	1.59	1.00-2.52	.05	0.95	0.66-1.37	.80	0.70	0.42-1.19	.19	1.07	0.76-1.51	.69
Very poor	82	5.19	3.42-7.87	<.0001	3.05	2.26-4.11	<.0001	2.54	1.66-3.88	<.0001	3.59	2.67-4.83	<.0001

Cytogenetic risk5	No. of patients†	Relapse			Overall mortality			Nonrelapse mortality			Treatment failure*
Cytogenetic risk5	No. of patients†	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Univariate model
Good	270	1			1			1			1
Intermediate	108	0.98	0.62-1.57	.94	1.11	0.82-1.50	.50	1.21	0.83-1.76	.33	1.11	0.83-1.49	.49
Poor	73	1.54	0.98-2.43	.06	0.98	0.68-1.41	.92	0.75	0.45-1.26	.28	1.09	0.78-1.53	.62
Very poor	82	5.07	3.40-7.56	<.0001	3.35	2.51-4.46	<.0001	2.95	1.97-4.41	<.0001	3.83	2.89-5.08	<.0001
Multivariable model adjusting for blast count, hemoglobin, platelet count, neutrophil count, and LDH
Good	270	1			1			1			1
Intermediate	108	0.94	0.58-1.51	.80	1.02	0.75-1.39	.89	1.08	0.74-1.59	.68	1.03	0.77-1.39	.83
Poor	73	1.59	1.00-2.52	.05	0.95	0.66-1.37	.80	0.70	0.42-1.19	.19	1.07	0.76-1.51	.69
Very poor	82	5.19	3.42-7.87	<.0001	3.05	2.26-4.11	<.0001	2.54	1.66-3.88	<.0001	3.59	2.67-4.83	<.0001

HR, hazard ratio.

Death or relapse.

Patients with very good cytogenetics are not included due to small numbers (n = 9); 2 patients with unknown cytogenetics.