Correlation of p53/p21 protein expression with TP53 alteration status
| . | Protein expression . | |||
|---|---|---|---|---|
| p53 positive (34 cases) . | p53 negative (29 cases) . | |||
| p53+/p21+ . | p53+/p21− . | p53−/p21+ . | p53−/p21− . | |
| TP53 alterations (n = 14) | 1/11 | 10/11 | 1/3 | 2/3 |
| Wild-type (n = 49) | 19/23 | 4/23 | 7/26 | 19/26 |
| Total (n = 63) | 20/34 | 14/34 | 8/29 | 21/29 |
| . | Protein expression . | |||
|---|---|---|---|---|
| p53 positive (34 cases) . | p53 negative (29 cases) . | |||
| p53+/p21+ . | p53+/p21− . | p53−/p21+ . | p53−/p21− . | |
| TP53 alterations (n = 14) | 1/11 | 10/11 | 1/3 | 2/3 |
| Wild-type (n = 49) | 19/23 | 4/23 | 7/26 | 19/26 |
| Total (n = 63) | 20/34 | 14/34 | 8/29 | 21/29 |
TP53 alterations include either mutation or deletion. Protein expression was identified by immunostaining of paraffin-embedded tissue.