Table 6 Autoimmune manifestations after... | American Society of Hematology

Table 6

Autoimmune manifestations after HSCT

Donor group, no. patients	Autoimmunity disease score before HSCT	Chimerism	Autoimmune manifestations after HSCT
MSD
1	5, AIHA, thrombocytopenia	Full	Thrombocytopenia*†
2	3	Full	Thrombocytopenia*†
3	3	Full	Autoimmune hypothyroidism
4	3	Mixed/split	Thrombocytopenia, autoimmune hypothyroidism*‡
5	4	Full	Addison disease
URD
1	5, AIHA	Mixed	Inflammatory bowel disease (plus 6 mo after HSCT until 5 y)
2	3	Mixed	Thrombocytopenia*
3	3	Split‡	Autoimmune hypothyroidism
4	3	Full	Thrombocytopenia*
5	3	Mixed	Neutropenia, thrombocytopenia*
6	5, vasculitis	Mixed	Vasculitis
7	5, aortic vasculitis	Full	Pericarditis, AIHA
8	4	Mixed	Autoimmune hypothyroidism
9	4	Mixed	Thrombocytopenia*
MMRD
1	5, AIHA, thrombocytopenia	Mixed	AIHA
2	5, AIHA, thrombocytopenia	Mixed	Thrombocytopenia*
3	5, AIHA, thrombocytopenia	Mixed	AIHA, thrombocytopenia*
4	4	Mixed	Vasculitis
5	4	Mixed	Thrombocytopenia*

Donor group, no. patients	Autoimmunity disease score before HSCT	Chimerism	Autoimmune manifestations after HSCT
MSD
1	5, AIHA, thrombocytopenia	Full	Thrombocytopenia*†
2	3	Full	Thrombocytopenia*†
3	3	Full	Autoimmune hypothyroidism
4	3	Mixed/split	Thrombocytopenia, autoimmune hypothyroidism*‡
5	4	Full	Addison disease
URD
1	5, AIHA	Mixed	Inflammatory bowel disease (plus 6 mo after HSCT until 5 y)
2	3	Mixed	Thrombocytopenia*
3	3	Split‡	Autoimmune hypothyroidism
4	3	Full	Thrombocytopenia*
5	3	Mixed	Neutropenia, thrombocytopenia*
6	5, vasculitis	Mixed	Vasculitis
7	5, aortic vasculitis	Full	Pericarditis, AIHA
8	4	Mixed	Autoimmune hypothyroidism
9	4	Mixed	Thrombocytopenia*
MMRD
1	5, AIHA, thrombocytopenia	Mixed	AIHA
2	5, AIHA, thrombocytopenia	Mixed	Thrombocytopenia*
3	5, AIHA, thrombocytopenia	Mixed	AIHA, thrombocytopenia*
4	4	Mixed	Vasculitis
5	4	Mixed	Thrombocytopenia*

AIHA indicates autoimmune hemolytic anemia.

Mean platelet volume: normal, detection of antiplatelet antibodies.

Splenectomy 20 and 19 months following HSCT, respectively.

Split chimerism.